Clinical Trial

Breast Cancer Research and Treatment

, Volume 106, Issue 3, pp 413-418

Validation of the simplified Chinese version of the FACT-B for measuring quality of life for patients with breast cancer

  • Chonghua WanAffiliated withFaculty of Public Health, Kunming Medical CollegeDept. of Biostatistics and Computational Biology, University of Rochester Email author 
  • , Dongmei ZhangAffiliated withDepartment of Management, Guangdong Pharmacy College
  • , Zheng YangAffiliated withFaculty of Public Health, Kunming Medical College
  • , Xin TuAffiliated withDepartment of Biostatistics and Computational Biology, University of Rochester
  • , Wan TangAffiliated withDepartment of Biostatistics and Computational Biology, University of Rochester
  • , Changyong FengAffiliated withDepartment of Biostatistics and Computational Biology, University of Rochester
  • , Hongyue WangAffiliated withDepartment of Biostatistics and Computational Biology, University of Rochester
  • , Xueliang TangAffiliated withOncological Hospital of Yunnan Province

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Abstract

The simplified Chinese version of the FACT-B was evaluated by QOL data measured from 376 patients with breast cancer. The results showed that test–retest reliability for five domains: physical well-being, social/family well-being, emotional well-being, functional well-being, additional concerns, and the overall scales and trial outcome index were 0.82, 0.85, 0.91, 0.86, 0.90, 0.84 and 0.91, 0.89 respectively. The internal consistency α for the five domains mentioned above were 0.85, 0.82, 0.84, 0.84 and 0.59 respectively. Correlation analysis, factor analysis and structural equation model showed good construct validity. Criterion-related validity was also confirmed using QLICP-BR as a criterion. The instrument can find the change of QOL for cancer patients after treatment. It’s concluded that the simplified Chinese version of FACT-B can be used to measure QOL for Chinese patients with breast cancer with good validity, reliability and responsiveness.

Keywords

Breast cancer FACT-B QLICP-BR Quality of life Instrument Structural equation model