Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis
- First Online:
- Cite this article as:
- Cailliez, M., Garaix, F., Rousset-Rouvière, C. et al. J Inherit Metab Dis (2006) 29: 763. doi:10.1007/s10545-006-0408-7
- 153 Downloads
Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.