Journal of Inherited Metabolic Disease

, Volume 29, Issue 6, pp 763–763

Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis

  • M. Cailliez
  • F. Garaix
  • C. Rousset-Rouvière
  • D. Bruno
  • I. Kone-Paut
  • J. Sarles
  • B. Chabrol
  • M. Tsimaratos
Short Report

DOI: 10.1007/s10545-006-0408-7

Cite this article as:
Cailliez, M., Garaix, F., Rousset-Rouvière, C. et al. J Inherit Metab Dis (2006) 29: 763. doi:10.1007/s10545-006-0408-7

Summary

Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.

Supplementary material

10545_2006_ESM_408.pdf (197 kb)
Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis

Copyright information

© SSIEM and Springer 2006

Authors and Affiliations

  • M. Cailliez
    • 1
  • F. Garaix
    • 1
  • C. Rousset-Rouvière
    • 1
  • D. Bruno
    • 1
  • I. Kone-Paut
    • 2
  • J. Sarles
    • 1
  • B. Chabrol
    • 1
  • M. Tsimaratos
    • 1
  1. 1.AP-HM Timone-EnfantsMarseilles Cedex 05France
  2. 2.Department of PediatricsHôpital de Bicetre, Le Kremlin BicetreParisFrance