Journal of Inherited Metabolic Disease

, Volume 29, Issue 2, pp 421-425

First online:

Principles of therapeutic liver repopulation

  • Markus GrompeAffiliated withOregon Stem Cell Center, Oregon Health & Science University Email author 

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Liver repopulation by transplanted hepatocytes is a promising approach for many inborn errors of metabolism. In this review, examples of liver repopulation in animals and the implications of these models for clinical cell transplantation will be discussed.