Biomedical Microdevices

, Volume 11, Issue 3, pp 625–631

An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care

Article

DOI: 10.1007/s10544-008-9272-6

Cite this article as:
Elman, N.M., Ho Duc, H.L. & Cima, M.J. Biomed Microdevices (2009) 11: 625. doi:10.1007/s10544-008-9272-6

Abstract

We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD3 (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD3 provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD3 are proposed.

Keywords

MEMS Drug delivery Trauma care Emergency Micro-implant Rapid delivery Ambulatory emergency care Cardiac device Bolus Subcutaneous Cardiac 

Supplementary material

10544_2008_9272_MOESM1_ESM.doc (210 kb)
ESM 1(DOC 209 KB)

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  1. 1.Department of Materials Science and EngineeringMassachusetts Institute of TechnologyCambridgeUSA

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