An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care
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- Elman, N.M., Ho Duc, H.L. & Cima, M.J. Biomed Microdevices (2009) 11: 625. doi:10.1007/s10544-008-9272-6
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We introduce the first implantable drug delivery system based on MEMS (Micro-Electro-Mechanical-Systems) technology specifically designed as a platform for treatment in ambulatory emergency care. The device is named IRD3 (implantable rapid drug delivery device) and allows rapid delivery of drugs. Vasopressin was used as a model drug for in vitro tests as it is a commonly used drug for cardiac resuscitation. Experimental results reveal that the IRD3 provides an effective method for rapid delivery without significant drug degradation. Several medical uses and delivery modalities for IRD3 are proposed.