Biomedical Microdevices

, Volume 7, Issue 2, pp 153–156

The Synthesis of GoldMag Nano-Particles and their Application for Antibody Immobilization

  • Yali Cui
  • Yani Wang
  • Wenli Hui
  • Zhifeng Zhang
  • Xiaofang Xin
  • Chao Chen
Article

DOI: 10.1007/s10544-005-1596-x

Cite this article as:
Cui, Y., Wang, Y., Hui, W. et al. Biomed Microdevices (2005) 7: 153. doi:10.1007/s10544-005-1596-x
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Abstract

Fe3O4/Au (GoldMag) particles with core/shell structure were synthesized by reduction of Au3+ with hydroxylamine in the presence of Fe3O4. The synthesized particles have an average size smaller than 100 nm in diameter with of superparemagnetic properties due to their Fe oxide cores. The particles show optical features with a plasmon resonance peak from 550, 570 to 590 nm correlating with increasing diameters from 50 nm, 70 nm to 100 nm.The GoldMag particles need only a single step for antibody immobilization and have high binding capacity for antibodies. These advantages permit improved methods of isolating and detecting biomolecules.

Fe3O4/Au nanopaticle antibody immobilization 

Copyright information

© Springer Science + Business Media, Inc. 2005

Authors and Affiliations

  • Yali Cui
    • 1
  • Yani Wang
    • 1
  • Wenli Hui
    • 3
  • Zhifeng Zhang
    • 2
  • Xiaofang Xin
    • 3
  • Chao Chen
    • 2
  1. 1.Biochip Research and Development CenterNorthwest UniversityXi’anP.R. China
  2. 2.National Engineering Research Center for Miniaturized Detection SystemsXi’anP.R. China
  3. 3.Shaanxi Lifegen Ltd.Xi’anP.R. China

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