Biochemistry (Moscow)

, Volume 70, Issue 4, pp 406–423

Molecular Mechanisms of Epigenetics

  • N. A. Tchurikov

DOI: 10.1007/s10541-005-0131-2

Cite this article as:
Tchurikov, N.A. Biochemistry (Moscow) (2005) 70: 406. doi:10.1007/s10541-005-0131-2


The main epigenetic mechanisms in regulation of gene expression are discussed. The definition of epigenetics and its specific mechanisms including DNA methylation and gene imprinting, modifications of nucleosomal histones associated with silencing or activation of gene transcription, RNA interference, chromosomal silencing, and the role of mobile elements are discussed.

Key words

epigeneticsimprintinghistone modificationschromosomal silencingheterochromatinPcG proteinsforum domainsRNA interferencesiRNAmiRNARISCRITSmobile elements

Copyright information

© MAIK “Nauka/Interperiodica” 2005

Authors and Affiliations

  • N. A. Tchurikov
    • 1
  1. 1.Engelhardt Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia