Cardiolipin in energy transducing membranes
- Cite this article as:
- Mileykovskaya, E., Zhang, M. & Dowhan, W. Biochemistry (Moscow) (2005) 70: 154. doi:10.1007/s10541-005-0095-2
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Cardiolipin is a phospholipid located exclusively in energy transducing membranes such as the bacterial cytoplasmic membrane and the inner membrane of mitochondria. It plays both a structural and a functional role in many multimeric complexes associated with these membranes. The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described.