In vitro selection of peptide aptamers with affinity to single-wall carbon nanotubes using a ribosome display
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- Li, Z., Uzawa, T., Tanaka, T. et al. Biotechnol Lett (2013) 35: 39. doi:10.1007/s10529-012-1049-6
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A ribosome display from a diverse random library was applied for selecting peptide aptamers with high binding affinity to single-wall carbon nanotubes (SWCNTs). The selected peptide aptamer bound to and solubilized SWCNTs more strongly than did the peptide aptamer selected by a phage display method reported previously, and more strongly than other commonly used organic surfactants. The fluorescence spectrum of this aptamer showed a red shift upon interaction with SWCNTs but circular dichroism spectroscopy did not show any significant difference between the presence or absence of SWCNT binding.