Biotechnology Letters

, Volume 34, Issue 12, pp 2161–2173

The yeast hypoxic responses, resources for new biotechnological opportunities

  • M. Isabel González Siso
  • Manuel Becerra
  • Mónica Lamas Maceiras
  • Ángel Vizoso Vázquez
  • M. Esperanza Cerdán
Review

DOI: 10.1007/s10529-012-1039-8

Cite this article as:
Siso, M.I.G., Becerra, M., Maceiras, M.L. et al. Biotechnol Lett (2012) 34: 2161. doi:10.1007/s10529-012-1039-8

Abstract

Recent advances in the knowledge of molecular mechanisms that control the adaptation to low oxygen levels in yeast and their biotechnological applications, including bioproduct synthesis, such as ethanol, glutathione or recombinant proteins, as well as pathogenic virulence, are reviewed. Possible pathways and target genes, which might be of particular interest for the improvement of biotechnological applications, are evaluated.

Keywords

Heme-sensingHypoxiaSterol-sensing molecularYeast bio-productionsYeast pathogen virulence

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • M. Isabel González Siso
    • 1
  • Manuel Becerra
    • 1
  • Mónica Lamas Maceiras
    • 1
  • Ángel Vizoso Vázquez
    • 1
  • M. Esperanza Cerdán
    • 1
  1. 1.Departamento de Biología Celular y Molecular, F. CienciasUniversidad de A CoruñaCoruñaSpain