Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli
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- Kang, Z., Wang, X., Li, Y. et al. Biotechnol Lett (2012) 34: 527. doi:10.1007/s10529-011-0794-2
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Small RNA (RyhB) was overexpressed artificially using an arabinose-inducible system in Escherichia coli and resulted in more succinate (7-fold) accumulation, which suggested that RyhB had a strong effect on sdhCDAB genes. Acetate was also increased indicating that RyhB had a comprehensive influence on glucose central metabolism. RyhB might therefore be useful for metabolic engineering of E. coli.