Biotechnology Letters

, Volume 29, Issue 4, pp 561–567

Electro-biosorptive accumulation for use in enhanced detection of fluorogenic tracers and the removal of toxic entities from dilute solutions

Original Research Paper

DOI: 10.1007/s10529-006-9286-1

Cite this article as:
Nomikou, N. & McHale, A.P. Biotechnol Lett (2007) 29: 561. doi:10.1007/s10529-006-9286-1


An accumulating process based on electric field-assisted biosorption is described to facilitate the accumulation and enhanced detection of organic fluorogenic marker species in aqueous solution. Fluorescein was detected at concentrations as low as 0.6 μg l−1. Using a mammalian cell-based bioassay, we demonstrate the use of the system to remove the toxic effects of species such as ethidium bromide and doxorubicin from complex solutions such as tissue culture medium. The use of such a system for the detection and removal of trace contaminants is discussed.


BiosorptionDetoxificationElectric fieldViability

Copyright information

© Springer Science+Business Media B.V. 2007

Authors and Affiliations

  1. 1.School of Biomedical SciencesUniversity of UlsterColeraine, Co DerryNorthern Ireland, UK
  2. 2.EFMB Ltd.Belfast, Co. AntrimNorthern Ireland, UK