BioControl

, Volume 57, Issue 3, pp 463–469

Metabolites from Pseudomonas brassicacearum with activity against the pink snow mould causing pathogen Microdochium nivale

  • Pierre F. Andersson
  • Jolanta Levenfors
  • Anders Broberg
Article

DOI: 10.1007/s10526-011-9411-5

Cite this article as:
Andersson, P.F., Levenfors, J. & Broberg, A. BioControl (2012) 57: 463. doi:10.1007/s10526-011-9411-5

Abstract

Bioassay-guided fractionation of cell-free culture supernatants of the bacterium Pseudomonas brassicacearum MA250 yielded three bioactive compounds (1–3). Compound 1 was identified as the unsaturated fatty acid γ-lactone piliferolide A, compound 2 as the not previously described open acid form of 1, and 3 as the compound SB-253514, which is an imide of a 3-O-rhamnosyl fatty acid and a bicyclic carbamate. All three compounds displayed moderate activity towards the pink snow mould causing pathogen Microdochium nivale, and may thus contribute to the previously observed biological control of this strain on M. nivale on wheat. Compound 1 further exhibited activity towards the human pathogen Aspergillus fumigatus, while compound 3 showed antifungal as well as antibacterial activity.

Keywords

AntibiosisAntifungalBiocontrolMicrobial antagonismMicrodochium nivale

Copyright information

© International Organization for Biological Control (IOBC) 2011

Authors and Affiliations

  • Pierre F. Andersson
    • 1
  • Jolanta Levenfors
    • 2
  • Anders Broberg
    • 1
  1. 1.Department of Chemistry, Uppsala BioCenterSwedish University of Agricultural SciencesUppsalaSweden
  2. 2.MASE Laboratories ABUppsalaSweden