Bulletin of Experimental Biology and Medicine

, Volume 152, Issue 1, pp 93–97

Psychoimmune Interactions in Women of Reproductive Age with Endometriosis

  • R. F. Nasyrova
  • L. S. Sotnikova
  • N. V. Baystrukova
  • G. V. Krivoschchekova
  • V. V. Novitsky
  • I. E. Kupriyanova
  • V. Ya. Semke
  • I. O. Naslednikova
  • A. N. Baykov
Article

DOI: 10.1007/s10517-011-1463-0

Cite this article as:
Nasyrova, R.F., Sotnikova, L.S., Baystrukova, N.V. et al. Bull Exp Biol Med (2011) 152: 93. doi:10.1007/s10517-011-1463-0

Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.

Key Words

psychoneuroimmunology mental disorders immune disorders endometriosis 

Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • R. F. Nasyrova
    • 1
  • L. S. Sotnikova
    • 2
  • N. V. Baystrukova
    • 2
  • G. V. Krivoschchekova
    • 2
  • V. V. Novitsky
    • 2
  • I. E. Kupriyanova
    • 1
  • V. Ya. Semke
    • 1
  • I. O. Naslednikova
    • 2
  • A. N. Baykov
    • 2
  1. 1.Institute of Mental HealthSiberian Division of the Russian Academy of Medical SciencesTomskRussia
  2. 2.Siberian State Medical University, Federal Agency for Health Care and Social DevelopmentTomskRussia

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