, Volume 150, Issue 4, pp 468-470
Date: 08 Mar 2011

Changes in Apoptosis and Cell Proliferation in Human Pineal Gland during Aging

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Immunohistochemical analysis of the expression of proapoptotic protein P53 and proliferation protein Ki-67 in human pineal gland showed that in people over 60 years pinealocyte proliferation is virtually absent. Moreover, pinealocyte apoptosis is more pronounced in elderly, whereas in senile and long-living individuals its intensity decreases.

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 150, No. 10, pp. 443-445, October, 2010