General Pathology and Pathophysiology

Bulletin of Experimental Biology and Medicine

, 148:191

First online:

Kinetic Parameters of Liver Aldehyde Dehydrogenase in Rats with Cold Injury

  • A. G. Solov’evaAffiliated withNizhny Novgorod Institute of Traumatology and Orthopedics, Federal Agency of High-Technology Medical Care Email author 
  • , Yu. V. ZiminAffiliated withNizhny Novgorod Institute of Traumatology and Orthopedics, Federal Agency of High-Technology Medical Care
  • , A. M. RazmakhovAffiliated withNizhny Novgorod Institute of Traumatology and Orthopedics, Federal Agency of High-Technology Medical Care

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We studied the kinetics of liver aldehyde dehydrogenase in rats with cold injury. Low-temperature exposure was followed by a decrease in activity and catalytic effi ciency of aldehyde dehydrogenase in rat liver mitochondria. Atypical changes in kinetic characteristics of aldehyde dehydrogenase were found in the cytoplasmic fraction during cold injury.

Key Words

kinetics aldehyde dehydrogenase liver cold injury