Immunopharmacological properties of noopept

  • L. P. Kovalenko
  • E. V. Shipaeva
  • S. V. Alekseeva
  • A. V. Pronin
  • A. D. Durnev
  • T. A. Gudasheva
  • R. U. Ostrovskaja
  • S. B. Seredenin
Article

DOI: 10.1007/s10517-007-0251-3

Cite this article as:
Kovalenko, L.P., Shipaeva, E.V., Alekseeva, S.V. et al. Bull Exp Biol Med (2007) 144: 49. doi:10.1007/s10517-007-0251-3
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Abstract

Noopept, a peptide analog of piracetam, enhanced phagocytic activity of mouse peritoneal macrophages, stimulated humoral and cellular immune response to various antigens, and markedly increased spontaneous proliferative activity of splenocytes. In animals with secondary immune deficiency caused by cyclophosphamide, noopept exhibited immunocorrector properties.

Key Words

noopept cyclophosphamide humoral and cellular immunity phagocytosis proliferative activity of splenocytes 

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • L. P. Kovalenko
    • 1
  • E. V. Shipaeva
    • 1
  • S. V. Alekseeva
    • 1
  • A. V. Pronin
    • 2
  • A. D. Durnev
    • 1
  • T. A. Gudasheva
    • 1
  • R. U. Ostrovskaja
    • 1
  • S. B. Seredenin
    • 1
  1. 1.V. V. Zakusov Institute of PharmacologyRussian Academy of Medical SciencesRussia
  2. 2.N. F. Gamaleya Institute of Epidemiology and MicrobiologyMoscow

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