Bulletin of Experimental Biology and Medicine

, Volume 140, Issue 6, pp 726–728

Analysis of restriction fragment length polymorphism of cytochrome P450 3A43 gene and evaluation of the incidence of CYP3A43*1B allele in europeoid residents of West Siberia

  • E. G. Shchepotina
  • M. V. Nikishina
  • V. A. Vavilin
  • V. V. Lyakhovich
Genetics

DOI: 10.1007/s10517-006-0067-6

Cite this article as:
Shchepotina, E.G., Nikishina, M.V., Vavilin, V.A. et al. Bull Exp Biol Med (2005) 140: 726. doi:10.1007/s10517-006-0067-6

Abstract

Analysis of restriction fragment length polymorphism is proposed for detecting CYP3A43 gene c1047>T mutation. The incidence of this mutation (CYP3A43*1B allele) was evaluated in 102 europeoid residents of West Siberia and it was found to be 12.25%.

Key Words

cytochrome P450 3A43genetic polymorphismanalysis of restriction fragment length polymorphism

Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  • E. G. Shchepotina
    • 1
  • M. V. Nikishina
    • 1
  • V. A. Vavilin
    • 1
  • V. V. Lyakhovich
    • 1
  1. 1.Institute of Molecular Biology and BiophysicsSiberian Division of Russian Academy of Medical SciencesNovosibirsk