Administration and Policy in Mental Health and Mental Health Services Research

, Volume 34, Issue 3, pp 221–232

Empirical Evaluation of the Generalizability of the Sample from the Multimodal Treatment Study for ADHD

  • Jack Stevens
  • Kelly Kelleher
  • Joel Greenhouse
  • Guanmin Chen
  • Huiyun Xiang
  • Eloise Kaizar
  • Peter S. Jensen
  • L. Eugene Arnold
Original Paper

DOI: 10.1007/s10488-006-0097-4

Cite this article as:
Stevens, J., Kelleher, K., Greenhouse, J. et al. Adm Policy Ment Health (2007) 34: 221. doi:10.1007/s10488-006-0097-4

Abstract

Randomized controlled trials (RCTs) are criticized for the questionable generalizability of their patient samples to real world populations. This study compared the demographic and clinical characteristics of children from the Multimodal Treatment Study of Children with ADHD (MTA) to those from the NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study and the National Health and Nutrition Examination Survey (NHANES). On the whole, we found no compelling evidence against the representativeness of the MTA sample, but the limited power from MECA and NHANES may have lead to noteworthy differences between datasets being statistically nonsignificant.

Keywords

ADHDExternal validityGeneralizability

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Jack Stevens
    • 1
  • Kelly Kelleher
    • 1
  • Joel Greenhouse
    • 2
  • Guanmin Chen
    • 3
  • Huiyun Xiang
    • 1
  • Eloise Kaizar
    • 2
  • Peter S. Jensen
    • 4
  • L. Eugene Arnold
    • 5
  1. 1.Department of PediatricsThe Ohio State UniversityColumbusUSA
  2. 2.Department of StatisticsCarnegie Mellon UniversityPittsburghUSA
  3. 3.School of Public HealthWuhan UniversityWuhanP.R. China
  4. 4.Department of Psychiatry, Center for the Advancement of Children’s Mental HealthColumbia UniversityNew YorkUSA
  5. 5.Department of PsychiatryThe Ohio State UniversityColumbusUSA