Applied Mathematics and Mechanics

, Volume 33, Issue 2, pp 165–176

Effects of renal artery stenosis on realistic model of abdominal aorta and renal arteries incorporating fluid-structure interaction and pulsatile non-Newtonian blood flow


DOI: 10.1007/s10483-012-1541-6

Cite this article as:
Mortazavinia, Z., Zare, A. & Mehdizadeh, A. Appl. Math. Mech.-Engl. Ed. (2012) 33: 165. doi:10.1007/s10483-012-1541-6


The effects of the renal artery stenosis (RAS) on the blood flow and vessel walls are investigated. The pulsatile blood flow through an anatomically realistic model of the abdominal aorta and renal arteries reconstructed from CT-scan images is simulated, which incorporates the fluid-structure interaction (FSI). In addition to the investigation of the RAS effects on the wall shear stress and the displacement of the vessel wall, it is determined that the RAS leads to decrease in the renal mass flow. This may cause the activation of the renin-angiotension system and results in severe hypertension.

Key words

renal artery stenosis (RAS) pulsatile fluid-structure interaction (FSI) non-Newtonian hypertension 

Chinese Library Classification


2010 Mathematics Subject Classification


Copyright information

© Shanghai University and Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Center for Research in Medical Physics and Engineering, School of MedicineShiraz University of Medical ScienceShirazIran
  2. 2.Young Researchers Club, Shiraz BranchIslamic Azad UniversityShirazIran