Original Paper

Antonie van Leeuwenhoek

, Volume 93, Issue 3, pp 305-313

First online:

Streptomyces sudanensis sp. nov., a new pathogen isolated from patients with actinomycetoma

  • Erika T. QuintanaAffiliated withSchool of Biology, University of NewcastleInstituto Politécnico Nacional (IPN), Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y Desarrollo (CIIEMAD)
  • , Katarzyna WierzbickaAffiliated withLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
  • , Pawel MackiewiczAffiliated withFaculty of Biotechnology, Department of Genomics, University of Wrocław
  • , Abdalla OsmanAffiliated withFaculty of Medicine, Mycetoma Research Centre, University of Khartoum
  • , Ahmed H. FahalAffiliated withFaculty of Medicine, Mycetoma Research Centre, University of Khartoum
  • , Mohamed E. HamidAffiliated withFaculty of Veterinary Science, Department of Preventive Medicine and Public Health, University of Khartoum
  • , Jolanta Zakrzewska-CzerwinskaAffiliated withLudwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
  • , Luis A. MaldonadoAffiliated withSchool of Biology, University of NewcastleInstituto de Ciencias del Mar y Limnología, Universidad Nacional Autónoma de México (UNAM)
  • , Michael GoodfellowAffiliated withSchool of Biology, University of Newcastle Email author 

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Abstract

Nine strains isolated from mycetoma patients and received as Streptomyces somaliensis were the subject of a polyphasic taxonomic study. The organisms shared chemical markers consistent with their classification in the genus Streptomyces and formed two distinct monophyletic subclades in the Streptomyces 16S rRNA gene tree. The first subclade contained four organisms, including the type strain of S. somaliensis, and the second clade the remaining five strains which had almost identical 16S rRNA sequences. Members of the two subclades were sharply separated using DNA:DNA relatedness and phenotypic data which also showed that the subclade 1 strains formed an heterogeneous group. In contrast, the subclade 2 strains were assigned to a single genomic species and had identical phenotypic profiles. It is evident from these data that the subclade 2 strains should be recognised as a new species of Streptomyces. The name proposed for this new species is Streptomyces sudanensis sp. nov. The type strain is SD 504T (DSM = 41923T = NRRL B-24575T).

Keywords

Mycetoma Polyphasic taxonomy Streptomyces