, Volume 58, Issue 3, pp 457-473
Date: 17 Jun 2006

Likelihood-based Inference for the Ratios of Regression Coefficients in Linear Models

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We consider the standard linear multiple regression model in which the parameter of interest is the ratio of two regression coefficients. Our setup includes a broad range of applications. We show that the 1− α confidence interval for the interest parameter based on the profile, conditional profile, modified profile or adjusted profile likelihood can potentially become the entire real line, while appropriately chosen integrated likelihoods do not suffer from this drawback. We further explore the asymptotic length of confidence intervals in order to compare integrated likelihood-based proposals. The analysis is facilitated by an orthogonal parameterization.