World Health Organization. PMTCT strategic vision 2010–2015: preventing mother-to-child transmission of HIV to reach the UNGASS and millennium development goals. http://www.who.int/hiv/pub/mtct/strategic_vision/en/index.html
. Published February 2, 2010. Accessed 10 March 2011.
UNAIDS Joint United Nations Programme on HIV/AIDS. UNAIDS report on the global AIDS epidemic 2010: epidemic update. http://www.unaids.org/globalreport/documents/20101123_globalreport_slides_chapter2_em.pdf
. Published November 23, 2010. Accessed 19 March 2011.
Onah HE, Obi SN, Agbata TA, Oguanuo TC. Pregnancy outcome in HIV-positive women in Enugu, Nigeria. J Obstet Gynaecol. 2007;27(3):271–4.
Rollins NC, Coovadia HM, Bland RM, et al. Pregnancy outcomes in HIV-infected and uninfected women in rural and urban South Africa. J Acquir Immune Defic Syndr. 2007;44(3):321–8.PubMedCrossRef
Le Coeur S, Khlat M, Halembokaka G, et al. HIV and the magnitude of pregnancy-related mortality in Pointe Noire, Congo. AIDS. 2005;19(1):69–75.PubMedCrossRef
Zijenah LS, Moulton LH, Iliff P, et al. Timing of mother-to-child transmission of HIV-1 and infant mortality in the first 6 months of life in Harare, Zimbabwe. AIDS. 2004;18(2):273–80.PubMedCrossRef
Gichuhi C, Obimbo E, Mbori-Ngacha D, et al. Predictors of mortality in HIV-1 exposed uninfected post-neonatal infants at the Kenyatta National Hospital, Nairobi. East Afr Med J. 2005;82(9):447–51.
Newell ML, Coovadia H, Cortina-Borja M, Rollins N, Gaillard P, Dabis F. Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis. Lancet. 2004;364(9441):1236–43.PubMedCrossRef
Doherty T, Chopra M, Nsibande D, Mngoma D. Improving the coverage of the PMTCT programme through a participatory quality improvement intervention in South Africa. BMC Public Health. 2009;9:406.PubMedCrossRef
US Agency of International Development Health Care Improvement Project. Quality improvement in HIV AIDS care, prevention of mother-to-child transmission, and related services. http://www.hciproject.org/node/1074
. Published November, 2008. Accessed 19 March 2011.
Levine R, Oomman N. Global HIV/AIDS funding and health systems: searching for the win-win. J Acquir Immune Defic Syndr. 2009;52(Suppl 1):S3–5.PubMedCrossRef
England R. Lessons and myths in the HIV/AIDS response. Lancet. 2009;374(9702):1674; author reply 1675–6.
England R. A strategic revolution in HIV and global health. Lancet. 2011;378(9787):226.PubMedCrossRef
Shiffman J. HIV/AIDS and the rest of the global health agenda. Bull World Health Organ. 2006;84(12):923.PubMedCrossRef
Shiffman J. Has donor prioritization of HIV/AIDS displaced aid for other health issues? Health Policy Plan. 2008;23(2):95–100.PubMedCrossRef
Starrs AM. Lessons and myths in the HIV/AIDS response. Lancet. 2009;374(9702):1674–5; author reply 1675–6.
Walsh A, Ndubani P, Simbaya J, Dicker P, Brugha R. Task sharing in Zambia: hIV service scale-up compounds the human resource crisis. BMC Health Serv Res. 2010;10:272.PubMedCrossRef
Furth R, Gass R, Kagubare J; US Agency for International Development. Rwanda human resources assessment for HIV AIDS services scale-up. http://pdf.usaid.gov/pdf_docs/PNADI710.pdf
. Published December 2006. Accessed 10 March 2011.
Medley AM, Kennedy CE. Provider challenges in implementing antenatal provider-initiated HIV testing and counseling programs in Uganda. AIDS Educ Prev. 2010;22(2):87–99.PubMedCrossRef
Lehmann U, Zulu J. Investigating the Impact of the HIV/AIDS epidemic on nurses in primary health care settings in Cape Town. The HIV/AIDS challenge in Africa: an impact and response assessment: the case of South Africa. 2008. http://hrh.uwc.ac.za/index.php?module=hrhlibrary&action=downloadfile&fileid=111930415946957
. Accessed 14 March 2011.
Lehmann U, Sanders D. Human Resource Development. In: Ijumba P, editor. South African health review 2002. Durban, South Africa: Health Systems Trust; 2002: http://www.hst.org.za/publications/south-african-health-review-2002
Druce N, Nolan A. Seizing the big missed opportunity: linking HIV and maternity care services in sub-Saharan Africa. Reprod Health Matters. 2007;15(30):190–201.PubMedCrossRef
El-Sadr WM, Abrams EJ. Scale-up of HIV care and treatment: can it transform healthcare services in resource-limited settings? AIDS. 2007;21:S65–70.PubMedCrossRef
Tudor Car L, van-Velthoven MH, Brusamento S, et al. Integrating prevention of mother-to-child HIV transmission (PMTCT) programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries. Cochrane Database Syst Rev. 2011(6):CD008741.
Dudley L, Garner P. Strategies for integrating primary health services in low- and middle-income countries at the point of delivery. Cochrane Database Syst Rev. 2011(7).
Both JM, van Roosmalen J. The impact of Prevention of Mother to Child Transmission (PMTCT) programmes on maternal health care in resource-poor settings: looking beyond the PMTCT programme—a systematic review. BJOG. 2010;117(12):1444–50.PubMedCrossRef
Rabkin M, El-Sadr WM, De Cock KM. Health system working group. The impact of HIV scale-up on health systems: a priority research agenda. J Acquir Immune Defic Syndr. 2009;52:S6–11.PubMedCrossRef
Deeks J, Higgins J, Altman D. Analysing and presenting results. In: Higgins J, Green S, editors. Cochrane handbook for systematic reviews of interventions 4.2.6 [updated September 2006]. Chichester: John Wiley & Sons, LTD; 2006. http://www.cochrane.org/resources/handbook/Handbook4.2.6Sep2006.pdf
Rutenberg N, Baek C, Kalibala S, Rosen J. Evaluation of United Nations-supported pilot projects for the prevention of mother-to-child transmission of HIV. Overview of findings. 2003:47.
Tudor Car L v-VM, Paljarvi T, Car J, Atun R. Integrating prevention of mother-to-child HIV transmission (PMTCT) programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries (Protocol). Cochrane Database Syst Rev. 2010(10).
Institute for Health Metrics and Evaluation. Development assistance for health estimates 1990–2010 update. Seattle: Institute for Health Metrics and Evaluation; 2010. http://www.healthmetricsandevaluation.org/ghdx/record/development-assistance-health-estimates-1990-2010-tables
. Accessed 19 March 2011.
United Nations. The millenium development goals report. http://www.un.org/millenniumgoals/pdf/MDG%20Report%202010%20En%20r15%20-low%20res%2020100615%20-.pdf
. Published June 15, 2010. Accessed 28 March 2011.
US Agency of International Development. Evidence-based interventions for major causes of maternal mortality. 2010. http://www.usaid.gov/our_work/global_health/mch/mh/techareas/maternal_mortality.html
. Accessed 27 March 2011.
Dabis F, Elenga N, Meda N, et al. 18-Month mortality and perinatal exposure to zidovudine in West Africa. AIDS. 2001;15(6):771–9.PubMedCrossRef
Chilongozi D, Wang L, Brown L, et al. Morbidity and mortality among a cohort of human immunodeficiency virus type 1-infected and uninfected pregnant women and their infants from Malawi, Zambia, and Tanzania. Pediatr Infect Dis J. 2008;27(9):808–14.PubMedCrossRef
Pattinson RC, HulsbeRgen MH, Van Hoorick L. The effect of maternal HIV infection on maternal conditions and perinatal deaths in southwest Tshwane. Facts Views Vision ObGyn. 2010;2(4).
Kurewa EN, Gumbo FZ, Munjoma MW, et al. Effect of maternal HIV status on infant mortality: evidence from a 9-month follow-up of mothers and their infants in Zimbabwe. J Perinatol. 2010;30(2):88–92.PubMedCrossRef
Townsend CL, Tookey PA, Newell ML, Cortina-Borja M. Antiretroviral therapy in pregnancy: balancing the risk of preterm delivery with prevention of mother-to-child HIV transmission. Antivir Ther. 2010;15(5):775–83.PubMedCrossRef
Spaulding AB, Brickley DB, Kennedy C, et al. Linking family planning with HIV/AIDS interventions: a systematic review of the evidence. AIDS. 2009;23(Suppl 1):S79–88.PubMedCrossRef
Kaai S, Baek C, Geibel S, et al. Community-based approaches to prevention of mother-to-child transmission of HIV: findings from a low-income community in Kenya. Horizons final report. 2007. http://www.popcouncil.org/pdfs/horizons/KenyaCommunityPMTCT.pdf
. Accessed 14 March 2011.
Kasenga F, Byass P, Emmelin M, Hurtig AK. The implications of policy changes on the uptake of a PMTCT programme in rural Malawi: first three years of experience. Glob Health Action. 2009;2.
Price JE, Leslie JA, Welsh M, Binagwaho A. Integrating HIV clinical services into primary health care in Rwanda: a measure of quantitative effects. AIDS Care. 2009;21(5):608–14.PubMedCrossRef
Creek TL, Ntumy R, Seipone K, et al. Successful introduction of routine opt-out HIV testing in antenatal care in Botswana. J Acquir Immune Defic Syndr. 2007;45(1):102–7.PubMedCrossRef
Delva W, Yard E, Luchters S, et al. A safe motherhood project in Kenya: assessment of antenatal attendance, service provision and implications for PMTCT. Trop Med Int Health. 2010;15(5):584–91.PubMedCrossRef
Brugha R, Simbaya J, Walsh A, Dicker P, Ndubani P. How HIV/AIDS scale-up has impacted on non-HIV priority services in Zambia. BMC Publ Health. 2010;10:540.
Lim Y, Kim JY, Rich M, et al. Improving prevention of mother-to-child transmission of HIV care and related services in eastern Rwanda. PLoS Med. 2010;7(7):e1000302.PubMedCrossRef
Magoni M, Okong P, Bassani L, Namaganda PK, Onyango S. Implementation of a programme for the prevention of mother-to-child transmission of HIV in a Ugandan hospital over five years: challenges, improvements and lessons learned. Int J STD AIDS. 2007;18(2):109–13.PubMedCrossRef
Chandisarewa W, Stranix-Chibanda L, Chirapa E, et al. Routine offer of antenatal HIV testing (“opt-out” approach) to prevent mother-to-child transmission of HIV in urban Zimbabwe. Bull World Health Organ. 2007;85(11):843–50.PubMed
Youngleson MS, Nkurunziza P, Jennings K, et al. Improving a mother to child HIV transmission programme through health system redesign: quality improvement, protocol adjustment and resource addition. PLoS ONE. 2010;5(11):e13891.PubMedCrossRef
Delvaux T, Konan JP, Ake-Tano O, et al. Quality of antenatal and delivery care before and after the implementation of a prevention of mother-to-child HIV transmission programme in Cote d’Ivoire. Trop Med Int Health. 2008;13(8):970–9.PubMedCrossRef
Tann CJ, Kizza M, Morison L, et al. Use of antenatal services and delivery care in Entebbe, Uganda: a community survey. BMC Pregnancy and Childbirth. 2007;7(1):23.PubMedCrossRef
Chege J, Askew I, Mosery N, et al. Feasibility of introducing a comprehensive package of antenatal care services in rural public clinics in South Africa. FRONTIERS final report. 2005. http://www.popcouncil.org/pdfs/frontiers/FR_FinalReports/SA_ANC.pdf
. Accessed 14 March 2011.
Population Council. Empowering communities to respond to HIV/AIDS: Ndola Demonstration Project on Maternal and Child Health: operations research final report. Horizons final report. 2003. http://www.popcouncil.org/pdfs/horizons/ndolafnl.pdf
. Accessed 14 March 2011.
Matsubayashi T, Manabe YC, Etonu A, et al. The effects of an HIV project on HIV and non-HIV services at local government clinics in urban Kampala. BMC Int Health Hum Rights. 2011;11(suppl 1).
Goldstein M, Zivin JG, Habyarimana J, Pop-Eleches C, Thirumurthy H. Health worker absence, HIV testing and behavioral change: evidence from western Kenya (working paper). 2010. http://www.columbia.edu/~cp2124/papers/anc.pdf
. Accessed 12 January 2012.
Besser M, Paruk F, Dinat N. Changing obstetric practices in the context of HIV: An evaluation of service provision in the national PMTCT learning sites. Durban, South Africa: Health Systems Trust and South Africa Department of Health; 2002. http://www.healthlink.org.za/uploads/files/pmtctobs.pdf
. Accessed 23 March 2011.
World Health Organization. Family planning for health and development: actions for change. 2010. http://www.who.int/reproductivehealth/publications/family_planning/fp_health_dvlpt/en/index.html
. Accessed 11 April 2011.
Tavengwa NV, Piwoz EG, Iliff PJ, et al. Adoption of safer infant feeding and postpartum sexual practices and their relationship to maternal HIV status and risk of acquiring HIV in Zimbabwe. Trop Med Int Health. 2007;12(1):97–106.PubMedCrossRef
World Health Organization. Standards for maternal and neonatal care: Provision of effective antenatal care. 2007. http://www.who.int/entity/reproductivehealth/publications/maternal_perinatal_health/effective_antenatal_care.pdf
. Accessed 10 April 2011.
Potter D, Goldenberg RL, Chao A, et al. Do targeted HIV programs improve overall care for pregnant women?: antenatal syphilis management in Zambia before and after implementation of prevention of mother-to-child HIV transmission programs. J Acquir Immune Defic Syndr. 2008;47(1):79–85.PubMedCrossRef
World Health Organization, Department of Reproductive Health and Research. Partner brief: advancing MDGs 4, 5 and 6: impact of congenital syphilis elimination. 2006. http://www.who.int/reproductivehealth/publications/rtis/rhr_hrp_10_01/en/index.html
. Accessed 27 March 2011.
Jackson DJ, Chopra M, Doherty TM, et al. Operational effectiveness and 36 week HIV-free survival in the South African programme to prevent mother-to-child transmission of HIV-1. AIDS. 2007;21(4):509–16.PubMedCrossRef
Manzi M, Zachariah R, Teck R, et al. High acceptability of voluntary counselling and HIV-testing but unacceptable loss to follow up in a prevention of mother-to-child HIV transmission programme in rural Malawi: scaling-up requires a different way of acting. Trop Med Int Health. 2005;10(12):1242–50.PubMedCrossRef
Rollins N, Little K, Mzolo S, Horwood C, Newell ML. Surveillance of mother-to-child transmission prevention programmes at immunization clinics: the case for universal screening. AIDS. 2007;21(10):1341–7.PubMedCrossRef
Ahoua L, Ayikoru H, Gnauck K, et al. Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda. J Trop Pediatr. 2010;56(1):43–52.PubMedCrossRef
Horwood C, Haskins L, Vermaak K, Phakathi S, Subbaye R, Doherty T. Prevention of mother to child transmission of HIV (PMTCT) programme in KwaZulu-Natal, South Africa: an evaluation of PMTCT implementation and integration into routine maternal, child and women’s health services. Trop Med Int Health. 2010;15(9):992–9.PubMed
Population Council. Strengthening PMTCT programs. Studies explore strategies to promote adherence and follow-up care. Horizons report. 2007:1–12. http://www.k4health.org/ar/popline/strengthening-pmtct-programs-studies-explore-strategies-promote-adherence-and-follow-care
. Accessed 10 March 2011.
Bwirire LD, Fitzgerald M, Zachariah R, et al. Reasons for loss to follow-up among mothers registered in a prevention-of-mother-to-child transmission program in rural Malawi. Trans R Soc Trop Med Hyg. 2008;102(12):1195–200.PubMedCrossRef
Panditrao M, Darak S, Kulkarni V, Kulkarni S, Parchure R. Socio-demographic factors associated with loss to follow-up of HIV-infected women attending a private sector PMTCT program in Maharashtra, India. AIDS Care. 2011;23(5):593–600.
Kaplan R, Orrell C, Zwane E, Bekker LG, Wood R. Loss to follow-up and mortality among pregnant women referred to a community clinic for antiretroviral treatment. AIDS. 2008;22(13):1679–81.PubMedCrossRef
Oladokun RE, Awolude O, Brown BJ, et al. Service uptake and performance of the prevention of mother-to-child transmission (PMTCT) programme in Ibadan, Nigeria. Afr J Med Med Sci. 2010;39(2):81–7.PubMed
Perez F, Mukotekwa T, Miller A, et al. Implementing a rural programme of prevention of mother-to-child transmission of HIV in Zimbabwe: first 18 months of experience. Trop Med Int Health. 2004;9(7):774–83.PubMedCrossRef
UNICEFChildInfo. HealthSystems 20/20 health systems database. Bethesda, MD: Abt Associates; 2010. http://healthsystems2020.healthsystemsdatabase.org
. Accessed 27 March 2011.
Leroy V, Karon JM, Alioum A, et al. Twenty-four month efficacy of a maternal short-course zidovudine regimen to prevent mother-to-child transmission of HIV-1 in West Africa. AIDS. 2002;16(4):631–41.PubMedCrossRef
Vithayasai V, Moyle GJ, Supajatura V, et al. Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission. J Acquir Immune Defic Syndr. 2002;30(4):410–2.PubMed
Lallemant M, Jourdain G, Le Coeur S, et al. Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in Thailand. N Engl J Med. 2004;351(3):217–28.PubMedCrossRef
Perinatal zidovudine plus nevirapine results in similar rates of mother-to-child transmission of HIV compared with nevirapine alone. Evid Healthc Publ Health. 2005;9(1):32–33.
Bonda V, Chaseb E, Aggleton P. Stigma, HIV/AIDS and prevention of mother-to-child transmission in Zambia. Eval Program Plann. 2002;25(4):347–56.CrossRef
Larsson EC, Thorson A, Nsabagasani X, Namusoko S, Popenoe R, Ekstrom AM. Mistrust in marriage–reasons why men do not accept couple HIV testing during antenatal care- a qualitative study in eastern Uganda. BMC Public Health. 2010;10:769.PubMedCrossRef
Thorsen VC, Sundby J, Martinson F. Potential initiators of HIV-related stigmatization: ethical and programmatic challenges for PMTCT programs. Dev World Bioeth. 2008;8(1):43–50.PubMedCrossRef
Nash D, Elul B, Rabkin M, et al. Strategies for more effective monitoring and evaluation systems in HIV programmatic scale-up in resource-limited settings: implications for health systems strengthening. J Acquir Immune Defic Syndr. 2009;52(Suppl 1):S58–62.PubMedCrossRef
Shakarishvili G, Lansang MA, Mitta V, et al. Health systems strengthening: a common classification and framework for investment analysis. Health Policy Plan. 2011;26(4):316–26.
Sundewall J, Swanson RC, Betigeri A, et al. Health-systems strengthening: current and future activities. Lancet. 2011;377(9773):1222–3.
The Foundation for AIDS Research. Issue brief: global health funding cuts in H.R. 1: Projecting the human cost. 2010. http://www.amfar.org/uploadedFiles/Articles/Articles/On_The_Hill/IBHR1rev.pdf?n=6988
. Accessed 27 March 2011.
Obama B. Statement by the president on global health initiative [press release]. Washington: The White House Office of the Press Secretary; May 5, 2009. http://www.whitehouse.gov/the_press_office/Statement-by-the-President-on-Global-Health-Initiative/
. Accessed 20 March 2011.
GOP’s Proposed Cuts To Africa Aid Criticized [transcript]. Morning edition. National Public Radio. February 17, 2011.
Abdullah MF, Young T, Bitalo L, Coetzee N, Myers JE. Public health lessons from a pilot programme to reduce mother-to-child transmission of HIV-1 in Khayelitsha. S Afr Med J. 2001;91(7):579–83.PubMed
Seipone K, Nturny R, Thuku H, Mazhani L, Shaffer N. Introduction of routine HIV testing in prenatal care—Botswana, 2004. Morbity Mortality Weekly Rep. 2004;53(46):1083–6.