AIDS and Behavior

, Volume 15, Issue 8, pp 1721–1731

An Interrupted Time Series Evaluation of a Hepatitis C Intervention for Persons with HIV

  • Rae Jean Proeschold-Bell
  • Bettina Hoeppner
  • Baishakhi Taylor
  • Sarah Cohen
  • Rachel Blouin
  • Beth Stringfield
  • Andrew J. Muir
Original Paper

DOI: 10.1007/s10461-010-9870-1

Cite this article as:
Proeschold-Bell, R.J., Hoeppner, B., Taylor, B. et al. AIDS Behav (2011) 15: 1721. doi:10.1007/s10461-010-9870-1

Abstract

Accurate HCV knowledge is lacking among high-risk groups, including people with HIV/AIDS (PLWHA). Liver disease primarily due to HCV has emerged as a serious cause of mortality among PLWHA. We used an Interrupted Time Series design to evaluate a social-ecologically based intervention for PLWHA, where an infectious disease clinic serving a six-county intervention area was monitored before (7 months) and after (17 months) intervention onset. The intervention included education of PLWHA and medical providers, HIV/HCV support groups, and adaptation of the patient chart top sheet to include HCV test information. Clinic-level outcomes were assessed prospectively every other week for 2 years by interviewing patients (n = 259) with clinic appointments on assessment days. Abrupt, gradual and delayed intervention effects were tested. Weighted regression analyses showed higher average HCV knowledge and a higher prevalence of patients reporting HCV discussion with their medical providers after intervention onset. A delayed effect was found for HCV awareness, and a gradually increasing effect was found for knowing one’s HCV status. Other communities may consider adopting this intervention. Additional HCV interventions for PLWHA with HIV are needed.

Keywords

HIV Hepatitis C Intervention research Prevention Interrupted Time Series 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Rae Jean Proeschold-Bell
    • 1
  • Bettina Hoeppner
    • 2
  • Baishakhi Taylor
    • 3
  • Sarah Cohen
    • 4
  • Rachel Blouin
    • 4
  • Beth Stringfield
    • 5
  • Andrew J. Muir
    • 6
  1. 1.Duke University Global Health Institute, Duke University Center for Health PolicyDuke UniversityDurhamUSA
  2. 2.Center for Addiction Medicine, Massachusetts General HospitalHarvard UniversityBostonUSA
  3. 3.North Carolina Consortium for South Asian StudiesDuke UniversityDurhamUSA
  4. 4.Duke Health Inequalities ProgramDuke UniversityDurhamUSA
  5. 5.Duke University Center for Health PolicyPiedmont HIV Health Care ConsortiumDurhamUSA
  6. 6.Duke Clinical Research Institute, Duke University School of MedicineDuke UniversityDurhamUSA

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