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An International Quality of Life Instrument to Assess Wellbeing in Adults Who are HIV-Positive: A Short Form of the WHOQOL-HIV (31 items)

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Abstract

Few cross-cultural measures are available to assess quality of life (QoL) in HIV/AIDS. A short form of the WHOQOL-HIV—the WHOQOL-HIV BREF—was developed and tested. Survey data from 1,923 HIV-positive adults (selected for age, gender and disease stage) were collected in 8 culturally diverse centres. The ‘best’ HIV-specific item was extracted from five HIV facets of the WHOQOL-HIV long form using information about item correlations with QoL, health and domains, item discriminant validity and centre problems. The five identified items were then integrated with the WHOQOL-BREF to complete the 31 item WHOQOL-HIV BREF. This short form shows good internal consistency reliability and discriminant validity for ‘known’ disease stages. Confirmatory Factor Analysis showed an overall good fit for a six domains model (Comparative Fit Index = 0.97), supporting scoring. Quality of life in different cultures is reported. A value of the WHOQOL-HIV short form is in monitoring QoL in multi-national clinical trials, and in clinical practice.

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Acknowledgments

This paper was prepared by Prof Suzanne Skevington and Dr Kathryn O’Connell on behalf of the WHOQOL-HIV Group which comprises a coordinating group of collaborating investigators in each of the field sites, and a panel of consultants. At WHO the project was directed by Dr R. Billington, Dr J. Orley and Dr S. Saxena with technical assistance from Ms M. Lotfy. The field work reported here was carried out at the following centres: Mr M. Bartos, Centre for the Study of Sexually Transmissible Disease, Faculty of Health Sciences, La Trobe University, Victoria, Australia; Dr P. Chandra, National Institute of Mental Health & Neurosciences (NIMHANS), Bangalore, India; Dr M. Fleck, Department of Psychiatry & Legal Medicine, University of the State of Rio Grande do Sul, Porto Alegre, Brazil; Dr L. Bun Hor, NCHADS, Ministry of Public Health, Phnom Penh, Cambodia; Dr R. Bhargava, Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India; Prof F. Starace, Consultation Psychiatry & Behavioural Epidemiology Service, Naples, Italy; Dr S. Pkhidenko, Dniepropetrovsk State Medical Academy, Dniepropetrovsk, Ukraine; Dr K. Meesapya, Branch of Preventative Mental Health Technical Development, Department of Mental Health, Ministry of Public Health, Bangkok, Thailand; Dr A. Haworth, Department of Psychiatry, University of Zambia, Lusaka, Zambia; Dr J. Mutimbirwa, Department of Psychiatry, University of Zimbabwe, Harare, Zimbabwe. Analysis was conducted at University of Bath, UK, and WHO Geneva. Further information on the WHOQOL can be obtained at http://www.who.ch\msa\mnh\ql.htm and http://www.bath.ac.uk/whoqol.

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Correspondence to Suzanne M. Skevington.

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O’Connell, K.A., Skevington, S.M. An International Quality of Life Instrument to Assess Wellbeing in Adults Who are HIV-Positive: A Short Form of the WHOQOL-HIV (31 items). AIDS Behav 16, 452–460 (2012). https://doi.org/10.1007/s10461-010-9863-0

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