AIDS and Behavior

, 12:974

Predictors of Attrition Among High Risk HIV-Infected Participants Enrolled in a Multi-Site Prevention Trial

  • Mallory O. Johnson
  • Samantha E. Dilworth
  • Torsten B. Neilands
  • Margaret A. Chesney
  • Mary Jane Rotheram-Borus
  • Robert H. Remien
  • Lance Weinhardt
  • Anke A. Ehrhardt
  • Stephen F. Morin
  • NIMH HLP team
Original Paper

DOI: 10.1007/s10461-007-9356-y

Cite this article as:
Johnson, M.O., Dilworth, S.E., Neilands, T.B. et al. AIDS Behav (2008) 12: 974. doi:10.1007/s10461-007-9356-y

Abstract

Retaining high-risk individuals is critical for HIV prevention trials. The current analyses examined predictors of trial dropout among HIV-infected men and women in a multi-site HIV prevention trial. Results indicated that dropouts (n = 74) were more likely to be younger, depressed, and not taking antiretroviral therapy (ART) than those who continued (n = 815). No other background, substance use, or transmission risk differences were found, suggesting no direct evidence of dropout bias on key outcomes. Efforts may be warranted for early detection and treatment of depression and for improving retention of younger participants and those not on ART.

Keywords

Clinical trialsPreventionRetentionDepression

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Mallory O. Johnson
    • 1
  • Samantha E. Dilworth
    • 1
  • Torsten B. Neilands
    • 1
  • Margaret A. Chesney
    • 1
    • 2
  • Mary Jane Rotheram-Borus
    • 3
  • Robert H. Remien
    • 4
  • Lance Weinhardt
    • 5
  • Anke A. Ehrhardt
    • 4
  • Stephen F. Morin
    • 1
  • NIMH HLP team
    • 6
  1. 1.University of CaliforniaSan FranciscoUSA
  2. 2.National Center for Complementary and Alternative MedicineNational Institutes of HealthLos AngelesUSA
  3. 3.University of CaliforniaLos AngelesUSA
  4. 4.Columbia UniversityColumbiaUSA
  5. 5.Medical College of WisconsinWisconsinUSA
  6. 6.RockvilleUSA