AIDS and Behavior

, Volume 12, Issue 6, pp 852–859

Determinants of High-Risk Sexual Behavior during Post-Exposure Prophylaxis to Prevent HIV Infection

  • Sarit A. Golub
  • Lisa Rosenthal
  • Daniel E. Cohen
  • Kenneth H. Mayer
Original Paper

DOI: 10.1007/s10461-007-9286-8

Cite this article as:
Golub, S.A., Rosenthal, L., Cohen, D.E. et al. AIDS Behav (2008) 12: 852. doi:10.1007/s10461-007-9286-8

Abstract

Men who have sex with men (MSM) receiving non-occupational post-exposure prophylaxis (NPEP) to prevent HIV transmission completed interview-assisted questionnaires regarding high-risk behavior in the 6 months prior to NPEP and during the 28-day NPEP period. 21% of participants reported unprotected sex during NPEP, and 11% reported unprotected sex with HIV-positive or HIV status unknown partners. In univariate analyses, unprotected sex during NPEP was associated with prevention fatigue, depression, loss of loved ones to HIV, and a history of engagement with HIV/AIDS service organizations, e.g., receiving services from an HIV-related agency, donating money to HIV-related causes, and reading HIV-related magazines. Logistic regression analyses revealed that the strongest predictor of risk-taking during NPEP was HIV engagement. These data underscore the importance of combining chemoprophylaxis with behavioral interventions that support risk-reduction. Such interventions should not assume that those most engaged with HIV/AIDS service organizations are less likely to engage in risk behavior.

Keywords

HIV preventionSexual behaviorGay and bisexual menPost-exposure prophylaxisCognitive disengagementRisk factors

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Sarit A. Golub
    • 1
    • 2
  • Lisa Rosenthal
    • 1
  • Daniel E. Cohen
    • 3
  • Kenneth H. Mayer
    • 3
    • 4
  1. 1.Queens College of the City University of New YorkFlushingUSA
  2. 2.Graduate Center of the City University of New YorkNew YorkUSA
  3. 3.Fenway Community HealthBostonUSA
  4. 4.Miriam Hospital/Brown UniversityProvidenceUSA