AIDS and Behavior

, 10:85

Disclosure of HIV Status and Adherence to Daily Drug Regimens Among HIV-infected Children in Uganda


    • CDC-Uganda, Global AIDS Program
    • Centers for Disease Control and Prevention, UgandaC/O Uganda Virus Research Institute
  • Emmanuel Luyirika
    • The Mildmay Centre, Uganda
  • David W. Purcell
    • Division of HIV/AIDS Prevention, National Center for HIV, STD and TB PreventionCenters for Disease Control and Prevention
  • Julia Downing
    • The Mildmay Centre, Uganda
  • Frank Kaharuza
    • CDC-Uganda, Global AIDS Program
  • Jonathan Mermin
    • CDC-Uganda, Global AIDS Program
  • Samuel Malamba
    • CDC-Uganda, Global AIDS Program
  • Rebecca Bunnell
    • CDC-Uganda, Global AIDS Program
Original Paper

DOI: 10.1007/s10461-006-9141-3

Cite this article as:
Bikaako-Kajura, W., Luyirika, E., Purcell, D. et al. AIDS Behav (2006) 10: 85. doi:10.1007/s10461-006-9141-3


Pediatric adherence to daily drug regimens has not been widely assessed in Africa where majority of HIV infected children live. Using in-depth interviews of 42 HIV-infected children taking ART and/or cotrimoxazole prophylaxis, and 42 primary caregivers, at a comprehensive HIV/AIDS clinic in Uganda, we evaluated their adherence experiences for purposes of program improvement. Daily drug regimens provided by the pediatric clinic included cotrimoxazole prophylaxis as well as ART and cotrimoxazole combined. Complete disclosure of HIV status by caregivers to children and strong parental relationships were related to good adherence. Structural factors including poverty and stigma were barriers to adherence even for children who had had complete disclosure and a supportive relationship with a parent. To ensure adherence to life-extending medications, our findings underscore the need for providers to support caregivers to disclose, provide on-going support and maintain open communication with HIV-infected children taking cotrimoxazole prophylaxis and ART.



Copyright information

© Springer Science+Business Media, Inc. 2006