Article

Angiogenesis

, Volume 13, Issue 2, pp 149-160

First online:

Non-invasive imaging of angiogenesis in head and neck squamous cell carcinoma

  • Jacobus F. A. JansenAffiliated withDepartment of Medical Physics, Memorial Sloan-Kettering Cancer CenterDepartment of Radiology, Memorial Sloan-Kettering Cancer Center
  • , Jason A. KoutcherAffiliated withDepartment of Medical Physics, Memorial Sloan-Kettering Cancer CenterDepartment of Radiology, Memorial Sloan-Kettering Cancer CenterDepartment of Medicine, Memorial Sloan-Kettering Cancer Center
  • , Amita Shukla-DaveAffiliated withDepartment of Medical Physics, Memorial Sloan-Kettering Cancer CenterDepartment of Radiology, Memorial Sloan-Kettering Cancer Center Email author 

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Abstract

Squamous cell carcinoma of the head and neck (HNSCC) is the seventh most common cancer in the United States. Angiogenesis, the process by which new blood vessels are formed, is an essential element at the basis of both tumor growth and metastases. This review discusses pertinent aspects of the role of imaging modalities in assessing angiogenesis and anti-angiogenic therapy in advanced HNSCC.

Keywords

Head and neck squamous cell carcinoma Angiogenesis Anti-angiogenic treatment Imaging techniques Magnetic resonance imaging Computed tomography Positron emission tomography Ultrasound Molecular imaging