Intermittent, moderate-intensity aerobic exercise for only eight weeks reduces arterial stiffness: evaluation by measurement of stiffness parameter and pressure–strain elastic modulus by use of ultrasonic echo tracking
Background and purpose
Aerobic exercise has been reported to be associated with reduced arterial stiffness. However, the intensity, duration, and frequency of aerobic exercise required to improve arterial stiffness have not been established. In addition, most reports base their conclusions on changes in pulse wave velocity, which is an indirect index of arterial stiffness. We studied the effects of short-term, intermittent, moderate-intensity exercise training on arterial stiffness based on measurements of the stiffness parameter (β) and pressure–strain elastic modulus (E p), which are direct indices of regional arterial stiffness.
A total of 25 young healthy volunteers (18 men) were recruited. By use of ultrasonic diagnostic equipment we measured β and E p of the carotid artery before and after 8 weeks of exercise training.
After exercise training, systolic pressure (P s), diastolic pressure (P d), pulse pressure, systolic arterial diameter (D s), and diastolic arterial diameter (D d) did not change significantly. However, the pulsatile change in diameter ((D s − D d)/D d) increased significantly, and β and E p decreased significantly.
For healthy young subjects, β and E p were reduced by intermittent, moderate-intensity exercise training for only 8 weeks.
- Arena, R, Fei, DY, Arrowood, JA, Kraft, KA (2007) Influence on aerobic fitness on aortic stiffness in apparently healthy Caucasian and African-American subjects. Int J Cardiol 122: pp. 202-206 CrossRef
- Madden, KM, Lockhart, C, Cuff, D, Potter, TF, Meneilly, GS (2009) Short-term aerobic exercise reduces arterial stiffness in older adults with type 2 diabetes, hypertension, and hypercholesterolemia. Diabetes Care 32: pp. 1531-1535 CrossRef
- Seals, DR, Walker, AE, Pierce, GL, Lesniewski, LA (2009) Habitual exercise and vascular ageing. J Physiol 587: pp. 5541-5549 CrossRef
- Cameron, JD, Dart, AM (1994) Exercise training increases total systemic arterial compliance in humans. Am J Physiol 266: pp. H693-H701
- Hambrecht, R, Fiehn, E, Weigl, C, Gielen, S, Hamann, C, Kaiser, R (1998) Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure. Circulation 98: pp. 2709-2715 CrossRef
- Liang, YL, Gatzka, CD, Du, XJ, Cameron, JD, Kingwell, BA, Dart, AM (1999) Effects of heart rate on arterial compliance in men. Clin Exp Pharmacol Physiol 26: pp. 342-346 CrossRef
- Williams, MR, Westerman, RA, Kingwell, BA, Paige, J, Blombery, PA, Sudhir, K (2001) Variations in endothelial function and arterial compliance during the menstrual cycle. J Clin Endocrinol Metab 86: pp. 5389-5395 CrossRef
- Harada, A, Okada, T, Niki, K, Chang, D, Sugawara, M (2002) On-line noninvasive one-point measurements of pulse wave velocity. Heart Vessels 17: pp. 61-68 CrossRef
- Yoon, ES, Jung, SJ, Cheun, SK, Oh, YS, Kim, SH, Jae, SY (2010) Effects of acute resistance exercise on arterial stiffness in young men. Korean Circ J 40: pp. 16-22 CrossRef
- Aizawa, K, Petrella, RJ (2008) Acute and chronic impact of dynamic exercise on arterial stiffness in older hypertensives. Open Cardiovasc Med J 2: pp. 3-8 CrossRef
- Niki, K, Sugawara, M, Chang, D, Harada, A, Okada, T, Sakai, R (2002) A new noninvasive measurement system for wave intensity: evaluation of carotid arterial wave intensity and reproducibility. Heart Vessels 17: pp. 12-21 CrossRef
- Kraft, KA, Itskovich, VV, Fei, DY (2001) Rapid measurement of aortic wave velocity: in vivo evaluation. Magn Reson Med 46: pp. 95-102 CrossRef
- Hayashi, K, Nagasawa, S, Naruo, Y, Okamura, A, Moritake, K, Handa, H (1980) Mechanical properties of human cerebral arteries. Biorheology 17: pp. 211-218
- Sugawara, M, Niki, K, Ohte, N, Okada, T, Harada, A (2009) Clinical usefulness of wave intensity analysis. Med Biol Eng Comput 47: pp. 197-206 CrossRef
- Tanaka, H, Dinenno, FA, Monahan, KD, Clevenger, CM, DeSouza, CA, Seals, DR (2000) Aging, habitual exercise, and dynamic arterial compliance. Circulation 102: pp. 1270-1275 CrossRef
- Joyner, MJ (2000) Effect of exercise on arterial compliance. Circulation 102: pp. 1214-1215 CrossRef
- Intermittent, moderate-intensity aerobic exercise for only eight weeks reduces arterial stiffness: evaluation by measurement of stiffness parameter and pressure–strain elastic modulus by use of ultrasonic echo tracking
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Journal of Medical Ultrasonics
Volume 40, Issue 2 , pp 119-124
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- Springer Japan
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- Arterial stiffness
- Echo tracking
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- Author Affiliations
- 1. Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo, 670-8524, Japan
- 2. Department of Medical Engineering, Kawasaki University of Medical Welfare, Kurashiki, Japan
- 3. Department of Biomedical Engineering, Tokyo City University, Tokyo, Japan