Clinical Investigation

Japanese Journal of Ophthalmology

, Volume 54, Issue 1, pp 19-23

First online:

Comparison of patients with ocular tuberculosis in the 1990s and the 2000s

  • Jun SuzukiAffiliated withDepartment of Ophthalmology, Tokyo Medical University HospitalDepartment of Ophthalmology, Tokyo Medical University Hospital Email author 
  • , Keiko Oh-IAffiliated withDepartment of Ophthalmology, Tokyo Medical University Hospital
  • , Takeshi KezukaAffiliated withDepartment of Ophthalmology, Tokyo Medical University Hospital
  • , Jun-ichi SakaiAffiliated withDepartment of Ophthalmology, Tokyo Medical University Hospital
  • , Hiroshi GotoAffiliated withDepartment of Ophthalmology, Tokyo Medical University Hospital

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Abstract

Purpose

To compare clinical findings in patients with ocular tuberculosis experienced during two different decades.

Methods

Thirty-four patients with ocular tuberculosis were divided into two groups: a 1990s group (n = 18) and a 2000s group (n = 16), according to the dates of their first outpatient visit. The clinical profiles of the two groups were then compared.

Results

More cases of the 1990s group had complications involving extraocular tuberculosis than those of the 2000s group. While various ophthalmic manifestations were observed clinically in the 1990s group, all retinal periphlebitis cases presented in the 2000s group. The proportion of patients who received antituberculous treatment was higher in the 1990s group, but the proportion who received oral corticosteroid therapy did not differ between the two periods. However, more patients underwent laser photocoagulation in the 2000s group. The percentage of eyes with final visual acuity better than 20/20 increased in the 2000s group.

Conclusions

The clinical outcome of patients with ocular tuberculosis was improved in the 2000s group, which may be attributable to the increase in active use of laser photocoagulation therapy.

Keywords

clinical manifestation prognosis treatment tuberculosis uveitis