Date: 16 Nov 2010

A historical perspective on the evolution of resting-state functional connectivity with MRI

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In this review article, I discuss initial and recent studies of the assessment of functional connectivity in the human brain using low-frequency BOLD fluctuations in the resting state. By putting the studies in their historical context, the goal is to give the reader an appreciation of the evolution of the field and the pivotal events and studies that have led to the widespread acceptance of the method as a neuroscience tool for investigating functional connectivity in the human brain.