, Volume 10, Issue 4, pp 240-244
Date: 19 Apr 2011

Enrichment and detection of circulating tumor cells in peripheral blood

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Abstract

Metastasis usually presents in the different courses of tumor diseases and associates with poor prognosis. Circulating tumor cells (CTC) are considered to be essential for conforming metastasis and can be detected in tumor patients’ peripheral blood. CTC are not easily detected by conventional cytology methods because of their low frequency in peripheral blood. Our article reviews the recent research results on this subject, and also discusses the problems and prospects in this area.