Review

Journal of Industrial Microbiology & Biotechnology

, Volume 38, Issue 4, pp 477-487

Enzyme catalysis with small ionic liquid quantities

  • Fabian FischerAffiliated withInstitute of Life Technologies, University of Applied Sciences Western Switzerland Email author 
  • , Julien MutschlerAffiliated withInstitute of Life Technologies, University of Applied Sciences Western Switzerland
  • , Daniel ZuffereyAffiliated withInstitute Systems Engineering, University of Applied Sciences Western Switzerland

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Abstract

Enzyme catalysis with minimal ionic liquid quantities improves reaction rates, stereoselectivity and enables solvent-free processing. In particular the widely used lipases combine well with many ionic liquids. Demonstrated applications are racemate separation, esterification and glycerolysis. Minimal solvent processing is also an alternative to sluggish solvent-free catalysis. The method allows simplified down-stream processing, as only traces of ionic liquids have to be removed.

Keywords

Enzyme catalysis Solvent free Ionic liquid Multiphase Coating