Clinical Autonomic Research

, Volume 17, Issue 6, pp 370–374

Sevoflurane anesthesia decreases cardiac vagal activity and heart rate variability

  • Chanannait Paisansathan
  • Michael Lee
  • William E. Hoffman
  • Peggy Wheeler
SHORT COMMUNICATION

DOI: 10.1007/s10286-007-0437-9

Cite this article as:
Paisansathan, C., Lee, M., Hoffman, W.E. et al. Clin Auton Res (2007) 17: 370. doi:10.1007/s10286-007-0437-9

Abstract

We evaluated cardiac vagal activity during sevoflurane anesthesia in neurosurgical patients. Heart rate variability was determined by power spectral analysis and entropy with the patient awake and during sevoflurane anesthesia. High frequency power (0.15–0.50 Hz) and heart rate entropy decreased during sevoflurane and these effects were significantly correlated (r = 0.71 ± 0.12, P < 0.05). The results confirm that cardiac vagal activity was the primary determinant of heart rate variability, which was attenuated by sevoflurane.

Key words

anesthesia sevoflurane heart rate variability sympathetic parasympathetic autonomic nervous system 

Copyright information

© Springer 2007

Authors and Affiliations

  • Chanannait Paisansathan
    • 1
  • Michael Lee
    • 1
  • William E. Hoffman
    • 1
  • Peggy Wheeler
    • 1
  1. 1.Anesthesiology DepartmentUniversity of Illinois at ChicagoChicagoUSA

Personalised recommendations