The effects of exercise training on myocardial adrenergic and muscarinic receptors
- Cite this article as:
- Barbier*, J., Reland*, S., Ville, N. et al. Clin Auton Res (2006) 16: 61. doi:10.1007/s10286-006-0312-0
We investigated the effects of exercise training on heart rate variability (HRV) and myocardial adrenergic and muscarinic receptors in rats. Exercise training induced a decrease in body mass while ventricular size remained unchanged, a development we considered as a relative cardiac hypertrophy. In addition, there was a reduction in the density of myocardial β1-adrenergic receptors. These structural changes were associated with functional adaptations, as illustrated by the increased response of the sinus node to sympathetic blockade.