Clinical Autonomic Research

, Volume 15, Issue 3, pp 219–222

The value of autonomic testing in postural tachycardia syndrome

  • Amer Al-Shekhlee
  • Judah R. Lindenberg
  • Rami N. Hachwi
  • Thomas C. Chelimsky
RESEARCH ARTICLE

DOI: 10.1007/s10286-005-0282-7

Cite this article as:
Al-Shekhlee, A., Lindenberg, J.R., Hachwi, R.N. et al. Clin Auton Res (2005) 15: 219. doi:10.1007/s10286-005-0282-7

Abstract

Postural tachycardia syndrome (POTS) is a fairly common condition that may or may not be associated with autonomic neuropathy. In a retrospective analysis, we compared two groups of patients based on clinical and autonomic criteria, those with POTS in isolation (POTS-Alone), and POTS with evidence of autonomic neuropathy (POTS-AN). Of 260 records reviewed, 57 patients met the criteria for POTS; 38 (67%) patients assigned to the POTS-Alone group and 19 (33%) patients assigned to the POTS-AN group. A decreased sweat output on the quantitative sudomotor axon reflex test is the most frequent abnormal finding in the POST-AN group suggesting sympathetic cholinergic neuropathy. Clinically, headache and gastrointestinal symptoms were more frequent among the POTS-AN group. Therefore, POTS may exist in isolation and may differ from those associated with AN.

Key words

autonomic neuropathypostural tachycardiasudomotor axon reflex test

Copyright information

© Steinkopff Verlag 2005

Authors and Affiliations

  • Amer Al-Shekhlee
    • 1
    • 2
  • Judah R. Lindenberg
    • 1
  • Rami N. Hachwi
    • 1
  • Thomas C. Chelimsky
    • 1
  1. 1.Dept. of NeurologyUniversity Hospitals of Cleveland, Case Western Reserve UniversityCleveland (OH)USA
  2. 2.University Hospitals of Cleveland, Case Western Reserve UniversityWestlake (OH) 44145USA