Journal of Digital Imaging

, Volume 23, Issue 5, pp 520–526

Effect of Dose Reduction on the Ability of Digital Mammography to Detect Simulated Microcalcifications

  • Mari Yakabe
  • Shuji Sakai
  • Hidetake Yabuuchi
  • Yoshio Matsuo
  • Takeshi Kamitani
  • Taro Setoguchi
  • Mayumi Cho
  • Masafumi Masuda
  • Masayuki Sasaki
Article

DOI: 10.1007/s10278-009-9203-y

Cite this article as:
Yakabe, M., Sakai, S., Yabuuchi, H. et al. J Digit Imaging (2010) 23: 520. doi:10.1007/s10278-009-9203-y
  • 77 Downloads

Abstract

The purpose of this article was to report the relationship between radiation dose and the ability of sentence digital mammography to detect microcalcifications. All images were acquired by computed radiography and an anthropomorphic breast phantom. The tube voltage and anode/filter combination used were 28 kVp and Mo/Mo. Simulated microcalcifications with an approximate diameter of 250–350 μm were positioned on the phantom. Groups of six microcalcifications were arranged in one of two patterns, a line cluster 1 cm long or a hexagonal cluster 4 mm wide. One of the six microcalcifications was removed to create a negative control. Each cluster was placed on 25 different points. Four levels of milliampere-second (mAs) values were applied: 100%, 50%, 25%, and 12.5%. Five staff radiologists participated in an observer performance test. All observers used a workstation with a 3-megapixel monochrome LCD monitor. The areas under the receiver-operating characteristics curves (AUC) were used to compare diagnostic performance among the four doses. The overall AUC scores were 0.97 with 100% mAs, 0.93 (n.s.) with 50%, 0.90 (p < 0.05) with 25%, and 0.81 (p < 0.01) with 12.5% mAs. Among the negative series, the percentage of images on which observers were able to identify the removed microcalcification point decreased from 88.8% with 100% mAs to 83.6% (n.s.) with 50%, 74.8% (p < 0.001) with 25%, and 67.2% (p < 0.001) with 12.5% mAs. A certain level of dose reduction in digital mammography may be an option.

Key words

Digital mammography computed radiography observer performance radiation dose ROC-based analysis phantoms imaging 

Copyright information

© Society for Imaging Informatics in Medicine 2009

Authors and Affiliations

  • Mari Yakabe
    • 1
  • Shuji Sakai
    • 1
  • Hidetake Yabuuchi
    • 2
  • Yoshio Matsuo
    • 2
  • Takeshi Kamitani
    • 2
  • Taro Setoguchi
    • 2
  • Mayumi Cho
    • 1
  • Masafumi Masuda
    • 3
  • Masayuki Sasaki
    • 1
  1. 1.Department of Health Sciences, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  2. 2.Department of Clinical Radiology, Graduate School of Medicine SciencesKyushu UniversityFukuokaJapan
  3. 3.Fujifilm MedicalTokyoJapan

Personalised recommendations