, Volume 10, Issue 6, pp 465-467
Date: 25 Sep 2009

Efficacy of oxygen inhalation in sumatriptan refractory “high altitude” cluster headache attacks

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We describe the case of a 40-year-old woman, affected by episodic cluster headache, who presented with a cluster headache triggered by exposure to high altitude. Her attacks were refractory to sumatriptan, very effective at sea level, but responded to oxygen. A pathophysiological mechanism is proposed.