Modern Rheumatology

, 16:143

Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females: findings from the KYSS study

  • Masakazu Washio
  • Takahiko Horiuchi
  • Chikako Kiyohara
  • Hiroko Kodama
  • Yoshifumi Tada
  • Toyoko Asami
  • Hiroki Takahashi
  • Gen Kobashi
  • Takashi Abe
  • Hisato Tanaka
  • Norihiko Nogami
  • Mine Harada
  • Hiroshi Tsukamoto
  • Saburo Ide
  • Kohei Nagasawa
  • Osamu Ushiyama
  • Takao Hotokebuchi
  • Kazushi Okamoto
  • Naomasa Sakamoto
  • Satoshi Sasaki
  • Yoshihiro Miyake
  • Tetsuji Yokoyama
  • Mitsuru Mori
  • Asae Oura
  • Yasuhisa Sinomura
  • Hiromu Suzuki
  • Motohisa Yamamoto
  • Yutaka Inaba
  • Masaki Nagai
ORIGINAL ARTICLE

DOI: 10.1007/s10165-006-0474-6

Cite this article as:
Washio, M., Horiuchi, T., Kiyohara, C. et al. Mod Rheumatol (2006) 16: 143. doi:10.1007/s10165-006-0474-6

Abstract

Many risk factors have been proposed for systemic lupus erythematosus (SLE). However, there is little information about the relationship between lifestyles and SLE in Japan. Two case control studies were conducted in Kyushu, southern Japan, and in Hokkaido, northern Japan, to examine the relationship between lifestyles and development of SLE in females. The participants were 78 patients and 329 controls in Kyushu and 35 patients and 188 controls in Hokkaido. Smoking was associated with an increased risk of SLE after adjusting for age in both regions. However, in Hokkaido, this association between smoking and SLE did not reach statistical significance after adjusting for alcohol drinking. The present study suggests that smoking may increase the risk of SLE among Japanese females.

Key words

EpidemiologyKYSS studyRisk factorsSystemic lupus erythematosus (SLE)

Copyright information

© Japan College of Rheumatology 2006

Authors and Affiliations

  • Masakazu Washio
    • 1
    • 3
  • Takahiko Horiuchi
    • 2
  • Chikako Kiyohara
    • 2
  • Hiroko Kodama
    • 3
  • Yoshifumi Tada
    • 4
  • Toyoko Asami
    • 4
  • Hiroki Takahashi
    • 1
  • Gen Kobashi
    • 5
  • Takashi Abe
    • 6
  • Hisato Tanaka
    • 7
  • Norihiko Nogami
    • 8
  • Mine Harada
    • 2
  • Hiroshi Tsukamoto
    • 2
  • Saburo Ide
    • 3
  • Kohei Nagasawa
    • 4
  • Osamu Ushiyama
    • 4
  • Takao Hotokebuchi
    • 4
  • Kazushi Okamoto
    • 9
  • Naomasa Sakamoto
    • 10
  • Satoshi Sasaki
    • 11
  • Yoshihiro Miyake
    • 12
  • Tetsuji Yokoyama
    • 13
  • Mitsuru Mori
    • 1
  • Asae Oura
    • 1
  • Yasuhisa Sinomura
    • 1
  • Hiromu Suzuki
    • 1
  • Motohisa Yamamoto
    • 1
  • Yutaka Inaba
    • 14
  • Masaki Nagai
    • 15
  1. 1.Sapporo Medical University School of MedicineSapporoJapan
  2. 2.Kyushu University Graduate School of Medical SciencesFukuokaJapan
  3. 3.Department of Community Health and Clinical EpidemiologySt. Mary’s CollegeKurumeJapan
  4. 4.Faculty of MedicineSaga UniversitySagaJapan
  5. 5.Hokkaido University Graduate School of MedicineSapporoJapan
  6. 6.Kushiro City General HospitalKushiroJapan
  7. 7.Tanaka HospitalSagaJapan
  8. 8.Wakakusuryouikuen HospitalTosuJapan
  9. 9.Aichi Prefectural College of Nursing and HealthNagoyaJapan
  10. 10.Hyogo College of MedicineNishinomiyaJapan
  11. 11.National Institute of Health and NutritionTokyoJapan
  12. 12.Fukuoka University School of MedicineFukuokaJapan
  13. 13.National Institute of Public HealthSaitamaJapan
  14. 14.Juntendo University School of MedicineTokyoJapan
  15. 15.Saitama Medical SchoolSaitamaJapan