Clinical and Experimental Nephrology

, Volume 17, Issue 5, pp 708–711

ANCA-associated vasculitis: report from Korea

Review Article The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012

DOI: 10.1007/s10157-012-0754-8

Cite this article as:
Kim, H.W. & Song, Y.W. Clin Exp Nephrol (2013) 17: 708. doi:10.1007/s10157-012-0754-8


We investigated the clinical features of Korean patients with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) by reviewing the literature. The characteristics of AAV in Korean patients were as follows: (1) granulomatous and limited disease is prevalent in granulomatosis with polyangiitis (Wegener’s) (GPA), (2) ANCA positivity is lower in GPA (56.6–68.9 %) and eosinophilic granulomatosis with polyangiitis (EGPA) (5.9–8.3 %), whereas it is higher in microscopic polyangiitis (MPA) (69–94 %), (3) C-ANCA/proteinase 3 (PR3)-ANCA positivity is 71.5–100 % in GPA and P-ANCA/myeloperoxidase (MPO)-ANCA positivity reached 94–100 % in patients with MPA, (4) renal involvement or progression to end-stage renal disease was lower in Korean patients with GPA and EGPA than in Caucasians with GPA and EGPA (according to data provided in reports). The data provided here may need to be confirmed in large-scale studies.


ANCAVasculitisGranulomatosis with polyangiitis (Wegener’s)Eosinophilic granulomatosis with polyangiitisMicroscopic polyangiitis

Supplementary material

10157_2012_754_MOESM1_ESM.docx (30 kb)
Supplementary material 1 (DOCX 29 kb)

Copyright information

© Japanese Society of Nephrology 2012

Authors and Affiliations

  1. 1.Division of Rheumatology, Department of Internal MedicineSeoul National University HospitalSeoulKorea
  2. 2.WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Medical Research InstituteSeoul National University College of MedicineSeoulKorea