International Journal of Clinical Oncology

, Volume 9, Issue 5, pp 398–402

Esophageal cancer with colonic metastasis successfully treated by chemoradiotherapy followed by chemotherapy with S-1 and cisplatin

  • Hiroaki Iwase
  • Toshihiko Indo
  • Masaaki Shimada
  • Tomoyuki Tsuzuki
  • Keiko Nakarai
  • Syogo Kaida
  • Reiko Doi
  • Masayuki Okeya
  • Eriko Kato
CASE REPORT

DOI: 10.1007/s10147-004-0412-6

Cite this article as:
Iwase, H., Indo, T., Shimada, M. et al. Int J Clin Oncol (2004) 9: 398. doi:10.1007/s10147-004-0412-6

Abstract

A 51-year-old man was hospitalized for evaluation of dysphagia and bloody stool. Gastrointestinal endoscopy showed esophageal cancer invading the gastric fundus. A metastatic lesion was demonstrated in the sigmoid colon. The patient agreed to have concurrent chemoradiotherapy for the primary lesion, followed by additional chemotherapy. The first course included 30 Gy of radiotherapy given over 3 weeks, together with daily oral administration of S-1 (80 mg/m2 per day) for 2 weeks, and a 24-h infusion of cisplatin (70 mg/m2) on day 8. After a second course of chemoradiotherapy, four additional courses of chemotherapy with S-1 and cisplatin were administered, at 4-week intervals. After the additional chemotherapy, gastroscopy and colonoscopy showed disappearance of both the primary and the metastatic lesions. One year after his initial hospitalization, no recurrence of either the primary or the metastatic tumor lesions is evident.

Key words

Esophageal cancer Colonic metastasis Chemoradiotherapy S-1 Cisplatin Complete response 

Copyright information

© The Japan Society of Clinical Oncology 2004

Authors and Affiliations

  • Hiroaki Iwase
    • 1
  • Toshihiko Indo
    • 1
  • Masaaki Shimada
    • 1
  • Tomoyuki Tsuzuki
    • 1
  • Keiko Nakarai
    • 1
  • Syogo Kaida
    • 1
  • Reiko Doi
    • 1
  • Masayuki Okeya
    • 1
  • Eriko Kato
    • 2
  1. 1.Department of GastroenterologyNagoya National HospitalNagoyaJapan
  2. 2.Department of RadiologyNagoya National HospitalNagoyaJapan