Neurosurgical Review

, 33:11

Massive hemorrhage in hemangioblastomas

Literature review

Authors

    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
  • Fernando Alarcón Rodríguez
    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
  • Belén Ferri Ñíguez
    • Department of PathologyVirgen de la Arrixaca University Hospital
  • Juan F. Martínez-Lage Sánchez
    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
  • Antonio López López-Guerrero
    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
  • Matías Felipe Murcia
    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
  • Antonio M. Ruíz-Espejo Vilar
    • Regional Service of NeurosurgeryVirgen de la Arrixaca University Hospital
Review

DOI: 10.1007/s10143-009-0217-1

Cite this article as:
Ros de San Pedro, J., Alarcón Rodríguez, F., Ferri Ñíguez, B. et al. Neurosurg Rev (2010) 33: 11. doi:10.1007/s10143-009-0217-1

Abstract

Massive hemorrhage is a very uncommon event among hemangioblastomas. Forty-four cases have been reported before this review. Thorough analysis of all reported cases on literature was accomplished. The majority presented as parenchymatous or subarachnoid bleedings. Subarachnoid hemorrhage was only associated with spinal hemangioblastomas, while parenchymatous bleedings were more, but not only, originated from cranial instances. Ventricular hemorrhage from a hemangioblastoma was exceptional, with only two previous cases bleeding directly into the ventricular compartment. To our knowledge, the illustrative case is the first one of pure tetraventricular hemorrhage from a hemangioblastoma. When hemangioblastoma bleeding occurs, it is usually the very first clinical presentation of a previously undetected tumor. Solid type, large size, and spinal–radicular locations are more frequently related to hemorrhage. Hemorrhage following hemangioblastoma embolization and the association of this tumor with other bleeding lesions, such as arteriovenous malformations and aneurysms, is also discussed.

Keywords

HemorrhageHemangioblastomaVentricular hemorrhageArteriovenous malformationAneurysmPreoperative embolization

Copyright information

© Springer-Verlag 2009