Gastric Cancer

, Volume 14, Issue 3, pp 234–241

Prognostic relevance of demographics and surgical practice for patients with gastric cancer in two centers: in Poland versus Germany

  • Radoslaw Jaworski
  • Elfriede Bollschweiler
  • Arnulf H. Holscher
  • Stefan P. Monig
  • Jaroslaw Skokowski
  • Jacek Zielinski
  • Maciej Swierblewski
  • Andrzej Kopacz
  • Janusz Jaskiewicz
Original Article

DOI: 10.1007/s10120-011-0036-2

Cite this article as:
Jaworski, R., Bollschweiler, E., Holscher, A.H. et al. Gastric Cancer (2011) 14: 234. doi:10.1007/s10120-011-0036-2

Abstract

Background

Although studies comparing the surgical treatment of gastric carcinoma in Japan and Western industrialized countries have revealed differing survival rates, no studies to date have been performed comparing Western and Eastern Europe. This study aimed to compare demographics and surgical practice as well as the related prognostic impact on gastric cancer patients treated in Poland and Germany.

Methods

This retrospective study included gastric cancer patients treated between 1999 and 2004 by surgical departments in Gdansk (Poland) and Cologne (Germany). Univariate and multivariate analyses of demographic, histopathological, surgical, and prognostic data were performed.

Results

Included were 117 patients from Gdansk and 130 patients from Cologne. The Cologne patients showed higher incidence rates of serious comorbidity, pT1 cancer, and distant metastasis than those from Gdansk. Indications for and frequency of selected surgical procedures differed significantly. D2-lymphadenectomy was performed in 89% of the Cologne patients, while D1-lymphadenectomy was done for 85% of the Gdansk patients. Univariate analysis yielded a 5-year survival rate of 28.3% for the Gdansk patients, and 40.3% for the Cologne patients (p = 0.056). Independent prognostic factors were pT category (p = 0.002), pN category (p < 0.001), pM category (p = 0.027), residual tumor (R) category (p = 0.004), age (p = 0.012), and number of resected lymph nodes (p = 0.005).

Conclusions

Significant differences of clinical and surgical parameters exist between gastric cancer patients treated in Poland and Germany. In addition to established independent prognostic factors, we found that survival improved with each additionally resected lymph node.

Keywords

Gastric cancer Germany Lymphadenectomy Poland Prognosis Surgical procedures 

Copyright information

© The Author(s) 2011

Authors and Affiliations

  • Radoslaw Jaworski
    • 1
  • Elfriede Bollschweiler
    • 2
  • Arnulf H. Holscher
    • 2
  • Stefan P. Monig
    • 2
  • Jaroslaw Skokowski
    • 1
  • Jacek Zielinski
    • 1
  • Maciej Swierblewski
    • 1
  • Andrzej Kopacz
    • 1
  • Janusz Jaskiewicz
    • 1
  1. 1.Department of Surgical OncologyMedical University of GdanskGdańskPoland
  2. 2.Department of General, Visceral and Cancer SurgeryUniversity of CologneCologneGermany

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