Original article

Gastric Cancer

, Volume 9, Issue 1, pp 19-25

Metastatic cancer to the stomach

  • Paulo Moacir de Oliveira CampoliAffiliated withDepartment of Digestive Endoscopy, Araújo Jorge Hospital of the Goiás Anticancer AssociationDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Flávio Hayato EjimaAffiliated withDepartment of Digestive Endoscopy, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Daniela Medeiros Milhomem CardosoAffiliated withDepartment of Digestive Endoscopy, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Osterno Queiroz da SilvaAffiliated withDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Jales Benevides Santana FilhoAffiliated withDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Paulo Adriano de Queiroz BarretoAffiliated withDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Márcio Martins MachadoAffiliated withDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , Eliane Duarte MotaAffiliated withDepartment of Pathology, Araújo Jorge Hospital of the Goiás Anticancer Association
  • , João Alves Araujo FilhoAffiliated withDepartment of Pathology, Araújo Jorge Hospital of the Goiás Anticancer Association
    • , Rita de Cássia G. AlencarAffiliated withDepartment of Pathology, Araújo Jorge Hospital of the Goiás Anticancer Association
    • , Orlando Milhomem da MotaAffiliated withDepartment of Gastrointestinal Oncology, Araújo Jorge Hospital of the Goiás Anticancer Association

Abstract

Background

Metastases in the stomach are rare. The increased use of esophagogastroduodenoscopy (EGD), associated with better treatment results for malignancies, requires them to be acknowledged. The aim of this study was to describe a series of cases of metastasis to the stomach, their primary sites, clinical and endoscopic features, treatment, and results.

Methods

Twenty cases were diagnosed between December 1999 and January 2004. Their analysis included symptomatology, macroscopic presentation, time from diagnosis of the primary tumor to the detection of the gastric metastasis, treatment approach, and survival.

Results

The primary sites were the esophagus, skin, lung, cervix, breast, sigmoid colon, and testis. The symptom most frequently requiring EGD was upper gastrointestinal bleeding. Ten patients showed concomitant metastases to other organs. The mean time between diagnosis of the primary tumor and diagnosis of gastric metastasis was 16 months (range, 0 to 56 months). Only seven patients were given some form of treatment after diagnosis of the gastric metastasis. The median survival was 4.75 months. Overall survival during the first year was 20% and survival was nil at 2 years.

Conclusions

Gastric metastasis marks advanced disease and the prognosis is poor. New advances in diagnosis and treatment are required for better results.

Key words

Gastrointestinal endoscopy Stomach neoplasms Neoplasm seeding Gastric metastasis