Lasers in Medical Science

, Volume 29, Issue 3, pp 1009–1015

Intense pulsed light versus benzoyl peroxide 5 % gel in treatment of acne vulgaris

  • Azmy Ahmed Abd El-latif
  • Faisal Abdel Aziz Hassan
  • Ahmed Rashad Elshahed
  • Amr Ghareeb Mohamed
  • Mohamed L. Elsaie
Original Article

DOI: 10.1007/s10103-013-1440-0

Cite this article as:
El-latif, A.A.A., Hassan, F.A.A., Elshahed, A.R. et al. Lasers Med Sci (2014) 29: 1009. doi:10.1007/s10103-013-1440-0

Abstract

Acne is a common disorder affecting the pilosebaceous unit. Despite many advances in the treatments of acne vulgaris the best option is still controversial as the pathogenesis of acne is rather complex, necessitating various combination therapies. The objective of this study is to compare the clinical efficacy of intense pulsed light therapy (IPL) versus benzoyl peroxide 5 % for the treatment of inflammatory acne. Fifty patients of both sexes, (15 males and 35 females) aged (18–27 years), with mild-to-severe acne and Fitzpatrick skin phototype IV were enrolled in this study. The patients were equally divided into two groups. The first group was treated by benzoyl peroxide while the second group was treated by IPL. For both therapies, patients experienced a significant reduction in the mean of the inflammatory lesion counts over the treatment period. Comparing the effects of both therapies, BP produced better results than IPL. The difference in the results was statistically significant at the midpoint of the study. However, this difference was insignificant at the end of study. Treatment with both benzoyl peroxide and IPL resulted in considerable improvement of the acne after 5 weeks of treatment. Comparing the effects of both therapies, BP produced better results than IPL. The difference in the results was statistically significant at the midpoint of the study. However, this difference was insignificant at the end of study.

Keywords

Intense pulsed lightAcneBenzoyl peroxide

Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Azmy Ahmed Abd El-latif
    • 1
  • Faisal Abdel Aziz Hassan
    • 1
  • Ahmed Rashad Elshahed
    • 1
  • Amr Ghareeb Mohamed
    • 1
  • Mohamed L. Elsaie
    • 2
  1. 1.Department of Dermatology, Venereology and Andrology, Faculty of MedicineAl-Azhar UniversityCairoEgypt
  2. 2.Department of Dermatology and VenereologyNational Research CentreCairoEgypt