Lasers in Medical Science

, Volume 21, Issue 3, pp 134–139

In vivo photoacoustic imaging of blood vessels with a pulsed laser diode

  • Roy G. M. Kolkman
  • Wiendelt Steenbergen
  • Ton G. van Leeuwen
Original Article

DOI: 10.1007/s10103-006-0384-z

Cite this article as:
Kolkman, R.G.M., Steenbergen, W. & van Leeuwen, T.G. Lasers Med Sci (2006) 21: 134. doi:10.1007/s10103-006-0384-z

Abstract

Photoacoustic imaging is a hybrid imaging modality that is based on the detection of acoustic waves generated by absorption of pulsed light by tissue chromophores such as hemoglobin in blood. For this technique, usually large and costly Q-switched Nd:YAG lasers are used. These lasers provide a pulse energy of at least several milliJoules. In search of alternative light sources, we investigated the use of a small and compact pulsed laser diode to image blood vessels. We proved that a pulsed laser diode can be applied for imaging blood vessels in vivo.

Keywords

Imaging techniquesUltrasoundBlood vessels

Copyright information

© Springer-Verlag London Limited 2006

Authors and Affiliations

  • Roy G. M. Kolkman
    • 1
  • Wiendelt Steenbergen
    • 1
  • Ton G. van Leeuwen
    • 1
    • 2
  1. 1.Biophysical Engineering, Institute for BioMedical Technology, Faculty of Science and TechnologyUniversity of TwenteEnschedeThe Netherlands
  2. 2.Laser Center, Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands