European Journal of Clinical Microbiology and Infectious Diseases

, Volume 18, Issue 12, pp 852–858

Prospective Study of Community-Acquired Pneumonia of Bacterial Etiology in Adults

Authors

  • N. Sopena
    • Department of Internal Medicine, Infectious Disease Unit, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet s/n, Badalona, CP 08916, Barcelona, Spain
  • M. Sabrià
    • Department of Internal Medicine, Infectious Disease Unit, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet s/n, Badalona, CP 08916, Barcelona, Spain
  • M. L. Pedro-Botet
    • Department of Internal Medicine, Infectious Disease Unit, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet s/n, Badalona, CP 08916, Barcelona, Spain
  • J. M. Manterola
    • Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
  • L. Matas
    • Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
  • J. Domínguez
    • Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
  • J. M. Modol
  • P. Tudela
    • Department of Emergency, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
  • V. Ausina
    • Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
  • M. Foz
    • Department of Internal Medicine, Infectious Disease Unit, Hospital Universitari Germans Trias i Pujol, Carretera de Canyet s/n, Badalona, CP 08916, Barcelona, Spain
Article

DOI: 10.1007/s100960050419

Cite this article as:
Sopena, N., Sabrià, M., Pedro-Botet, M. et al. EJCMID (1999) 18: 852. doi:10.1007/s100960050419

Abstract

 The aim of this study was to prospectively analyze the bacterial etiology of community-acquired pneumonia in adults in Spain. From May 1994 to February 1996, 392 episodes of CAP diagnosed in the emergency department of a 600-bed university hospital were studied. An etiological diagnosis based on noninvasive microbiological investigations was achieved in 228 cases (58%); 173 of these diagnoses were definitive and 55 probable. Streptococcus pneumoniae, which caused 23.9% of the episodes, was the predominant pathogen observed, followed by Chlamydia pneumoniae (13.5%) and Legionella pneumophila (12.5%). Other less frequent pathogens found were Haemophilus influenzae (2.3%), Pseudomonas aeruginosa (1.5%), Mycoplasma pneumoniae (1.3%), Coxiella burnetii (1%), Moraxella catarrhalis (2 cases), Nocardia spp. (2 cases), and Staphylococcus aureus (2 cases). Streptococcus pneumoniae was significantly more frequent in patients with underlying disease and/or age ≥60 years (28% vs 13%, P=0.002), while Legionella pneumophila was more frequent in patients below 60 years of age and without underlying disease (20% vs 9%, P=0.006). Likewise, Streptococcus pneumoniae and Legionella pneumophila were the most frequent etiologies in patients requiring admission to the intensive care unit, occurring in 29% and 26.3% of the patients, respectively. In addition to Streptococcus pneumoniae, other microorganisms such as Chlamydia pneumoniae and Legionella spp. should be seriously considered in adults with community-acquired pneumonia when initiating empiric treatment or ordering rapid diagnostic tests.

Copyright information

© Springer-Verlag Berlin Heidelberg 1999