European Journal of Clinical Microbiology and Infectious Diseases

, Volume 18, Issue 11, pp 814–818

Cutaneous Hyalohyphomycosis Caused by Paecilomyces lilacinus in an Immunocompetent Host Successfully Treated with Itraconazole: Case Report and Review

  • F. Gutiérrez-Rodero
  • M. Moragón
  • V. Ortiz de la Tabla
  • M. J. Mayol
  • C. Martín
Note

DOI: 10.1007/s100960050407

Cite this article as:
Gutiérrez-Rodero, F., Moragón, M., Ortiz de la Tabla, V. et al. EJCMID (1999) 18: 814. doi:10.1007/s100960050407

Abstract

Paecilomyces lilacinus is an emerging fungal pathogen that is highly resistant to many antifungal drugs. Skin and subcutaneous soft tissue infections caused by this organism are very unusual. Most cases occur in patients with impaired host defenses or following surgical procedures. There has been only one previous report of a histologically confirmed cutaneous infection due to Paecilomyces lilacinus in a patient without predisposing factors. Described here is the second histopathologically proven case of Paecilomyces lilacinus cutaneous infection in a healthy patient without any apparent portal of entry. Prolonged antifungal chemotherapy with itraconazole led to resolution of the skin lesion. This case of sporadic cutaneous infection due to Paecilomyces lilacinus is believed to be the first reported in Europe and the first histopathologically proven case successfully treated with itraconazole.

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • F. Gutiérrez-Rodero
    • 1
  • M. Moragón
    • 2
  • V. Ortiz de la Tabla
    • 3
  • M. J. Mayol
    • 4
  • C. Martín
    • 3
  1. 1.Servicio de Medicina Interna, Sección de Enfermedades Infecciosas, Hospital General Universitario de Elche, C) Huertos y Molinos S/N, E-03202 Elche, Alicante, Spain e-mail:fgutierrezr@medynet.comES
  2. 2.Sección de Dermatología, Hospital Universitario de San Juan, Carretera de Valencia S/N, E-03550 San Juan, Alicante, SpainES
  3. 3.Sección de Microbiología, Hospital Universitario de San Juan, Carretera de Valencia S/N, E-03550 San Juan, Alicante, SpainES
  4. 4.Sección de Anatomía Patológica, Hospital Universitario de San Juan, Carretera de Valencia S/N, E-03550 San Juan, Alicante, SpainES