Note

European Journal of Clinical Microbiology and Infectious Diseases

, Volume 18, Issue 9, pp 662-664

First online:

A Case of Disseminated Histoplasmosis Likely due to Infection from a Liver Allograft

  • F. BotterelAffiliated withDepartment of Parasitology and Mycology, Le Kremlin-Bicetre Hospital, 78 rue du Général Leclerc, Paris XI University, F-94275 Le Kremlin-Bicetre, France e-mail: francoise.botterel@bct.ap-hop-paris.fr
  • , S. RomandAffiliated withDepartment of Parasitology and Mycology, Le Kremlin-Bicetre Hospital, 78 rue du Général Leclerc, Paris XI University, F-94275 Le Kremlin-Bicetre, France e-mail: francoise.botterel@bct.ap-hop-paris.fr
  • , F. SalibaAffiliated withHepatobiliary Center, Paul Brousse Hospital, 14 Avenue Paul-Vaillant Couturier, F-94804 Villejuif, France
  • , M. ReynesAffiliated withLaboratory of Pathology, Paul Brousse Hospital, 14 Avenue Paul-Vaillant Couturier, F-94804 Villejuif, France
  • , H. BismuthAffiliated withHepatobiliary Center, Paul Brousse Hospital, 14 Avenue Paul-Vaillant Couturier, F-94804 Villejuif, France
  • , D. SamuelAffiliated withHepatobiliary Center, Paul Brousse Hospital, 14 Avenue Paul-Vaillant Couturier, F-94804 Villejuif, France
  • , P. BouréeAffiliated withDepartment of Parasitology and Mycology, Le Kremlin-Bicetre Hospital, 78 rue du Général Leclerc, Paris XI University, F-94275 Le Kremlin-Bicetre, France e-mail: francoise.botterel@bct.ap-hop-paris.fr

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

 Disseminated histoplasmosis in immunosuppressed patients rarely occurs in nonendemic areas. Reported here is a case of disseminated histoplasmosis in a patient who had undergone orthotopic liver transplantation and had never traveled outside of France. The infection was most likely transmitted via the liver allograft, since the organ donor had lived in an area highly endemic for the disease (French Guiana) 20 years earlier. Two years post-transplantation, none of the other patients who received allografts (heart, cornea, kidneys) from the same donor had developed signs of infection.