European Journal of Clinical Microbiology & Infectious Diseases

, Volume 33, Issue 3, pp 285–290

Pediatric norovirus infection

Review

DOI: 10.1007/s10096-013-1967-9

Cite this article as:
Esposito, S., Ascolese, B., Senatore, L. et al. Eur J Clin Microbiol Infect Dis (2014) 33: 285. doi:10.1007/s10096-013-1967-9

Abstract

Noroviruses (NoVs) are among the most frequent causes of acute pediatric gastroenteritis. Although the disease is often self-limiting and recovery is the rule, it constitutes an important health problem because of its highly contagious nature and the high rate of morbidity. NoVs are responsible for 47–96 % of outbreaks of acute pediatric gastroenteritis, and 5–36 % of sporadic cases. NoV-induced gastroenteritis is a frequent cause of hospitalization, and severe and sometimes fatal cases have been reported in immunocompromised children. The increasing recognition of NoVs as the cause of pediatric disease and the limited success in preventing outbreaks have led to consideration of vaccines. However, while awaiting the development of a vaccine, there is an urgent need for more epidemiological data concerning childhood NoV infection, including the impact of NoVs on different age groups, the possible etiological role of NoVs in infections other than gastroenteritis, and the socioeconomic impact of NoVs on households.

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • S. Esposito
    • 1
  • B. Ascolese
    • 1
  • L. Senatore
    • 1
  • C. Codecà
    • 1
  1. 1.Pediatric Clinic 1, Department of Pathophysiology and Transplantation, Fondazione IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoUniversità degli Studi di MilanoMilanItaly